1LEM

THE MONOSACCHARIDE BINDING SITE OF LENTIL LECTIN: AN X-RAY AND MOLECULAR MODELLING STUDY

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1lem.1	All beta proteins	Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	Legume lectins	Legume lectin	lentil (Lens culinaris ) [TaxId: 3864 ],	SCOPe (2.08)
B	d1lem.1	All beta proteins	Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	Legume lectins	Legume lectin	lentil (Lens culinaris ) [TaxId: 3864 ],	SCOPe (2.08)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.200	Mainly Beta	Sandwich	Jelly Rolls		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00139	Legume lectin domain (Lectin_legB)	Legume lectin domain	-	Domain
B	PF00139	Legume lectin domain (Lectin_legB)	Legume lectin domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	LECTIN	binding carbohydrate binding mannose binding monosaccharide binding small molecule binding cation binding manganese ion binding transition metal ion binding ion binding metal ion binding calcium ion binding	cellular response to stimulus response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cellular response to oxygen-containing compound cell communication cellular response to carbohydrate stimulus cellular response to chemical stimulus response to carbohydrate response to chemical cellular response to stimulus response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cellular response to oxygen-containing compound cell communication cellular response to carbohydrate stimulus cellular response to chemical stimulus response to carbohydrate response to chemical cellular process cellular response to organic substance signal transduction carbohydrate mediated signaling	-
B	LECTIN	binding carbohydrate binding mannose binding monosaccharide binding small molecule binding cation binding manganese ion binding transition metal ion binding ion binding metal ion binding calcium ion binding	cellular response to stimulus response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cellular response to oxygen-containing compound cell communication cellular response to carbohydrate stimulus cellular response to chemical stimulus response to carbohydrate response to chemical cellular response to stimulus response to organic substance regulation of biological process regulation of cellular process response to stimulus signaling biological regulation response to oxygen-containing compound cellular response to oxygen-containing compound cell communication cellular response to carbohydrate stimulus cellular response to chemical stimulus response to carbohydrate response to chemical cellular process cellular response to organic substance signal transduction carbohydrate mediated signaling	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	Homologous Superfamily
A	IPR001220	Legume lectin domain	Domain
A	IPR000985	Legume lectin, alpha chain, conserved site	Conserved Site
A	IPR016363	Legume lectin	Family
A	IPR019825	Legume lectin, beta chain, Mn/Ca-binding site	Binding Site
B	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	Homologous Superfamily
B	IPR001220	Legume lectin domain	Domain
B	IPR000985	Legume lectin, alpha chain, conserved site	Conserved Site
B	IPR016363	Legume lectin	Family
B	IPR019825	Legume lectin, beta chain, Mn/Ca-binding site	Binding Site

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.