Annotations: 1LBU

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1lbua1	All alpha proteins	PGBD-like	PGBD-like	Peptidoglycan binding domain, PGBD	Zn2+ DD-carboxypeptidase, N-terminal domain	(Streptomyces albus G ) [TaxId: 1962 ],	SCOPe (2.08)
A	d1lbua2	Alpha and beta proteins (a+b)	Hedgehog/DD-peptidase	Hedgehog/DD-peptidase	Muramoyl-pentapeptide carboxypeptidase	Zn2+ DD-carboxypeptidase C-terminal catalytic domain	(Streptomyces albus G ) [TaxId: 1962 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Peptidoglycan binding domain PGBD	8024382	4000784	SCOP2 (2022-06-29)
A	SCOP2 Family	Muramoyl-pentapeptide carboxypeptidase	8023353	4001391	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PGBD-like	8036761	3001357	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Hedgehog/DD-peptidase	8035733	3001458	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PG_binding_1	e1lbuA1	A: alpha arrays	X: PGBD-like (From Topology)	H: PGBD-like (From Topology)	T: PGBD-like	F: PG_binding_1	ECOD (1.6)
A	Peptidase_M15_3	e1lbuA2	A: a+b two layers	X: Hedgehog/DD-peptidase (From Topology)	H: Hedgehog/DD-peptidase (From Topology)	T: Hedgehog/DD-peptidase	F: Peptidase_M15_3	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.101.10	Mainly Alpha	Orthogonal Bundle	Muramoyl-pentapeptide Carboxypeptidase	domain 1	CATH (4.3.0)
A	3.30.1380.10	Alpha Beta	2-Layer Sandwich	Muramoyl-pentapeptide Carboxypeptidase	domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01471	Putative peptidoglycan binding domain (PG_binding_1)	Putative peptidoglycan binding domain	This domain is composed of three alpha helices [1]. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation [2]. This domain may have a general peptidoglycan binding function. This family is ...	This domain is composed of three alpha helices [1]. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation [2]. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins [3]. The domain is found to bind peptidoglycan experimentally [4].	Domain
A	PF08291	Peptidase M15 (Peptidase_M15_3)	Peptidase M15	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	MURAMOYL-PENTAPEPTIDE CARBOXYPEPTIDASE	peptidase activity zinc D-Ala-D-Ala carboxypeptidase activity catalytic activity, acting on a protein metallocarboxypeptidase activity hydrolase activity metallopeptidase activity exopeptidase activity catalytic activity metalloexopeptidase activity carboxypeptidase activity cation binding ion binding binding metal ion binding peptidase activity zinc D-Ala-D-Ala carboxypeptidase activity catalytic activity, acting on a protein metallocarboxypeptidase activity hydrolase activity metallopeptidase activity exopeptidase activity catalytic activity metalloexopeptidase activity carboxypeptidase activity cation binding ion binding binding metal ion binding small molecule binding	organic substance metabolic process organonitrogen compound metabolic process proteolysis metabolic process primary metabolic process protein metabolic process macromolecule metabolic process cellular component organization cell wall organization or biogenesis cell wall organization cellular process cellular component organization or biogenesis external encapsulating structure organization	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002477	Peptidoglycan binding-like	Domain
A	IPR036365	PGBD-like superfamily	Homologous Superfamily
A	IPR009045	Hedgehog signalling/DD-peptidase zinc-binding domain superfamily	Homologous Superfamily
A	IPR013230	Peptidase M15A, C-terminal	Domain
A	IPR036366	PGBD superfamily	Homologous Superfamily

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	zinc D-Ala-D-Ala carboxypeptidase M-CSA #585	The zinc D-Ala-D-Ala carboxypeptidase belongs to the peptidase M15 family and hydrolyses the C-terminal peptide bond of the peptides of general structure R-DAla-D-Xaa, it is secreted by Streptomyces albus G. The lytic activity of the enzyme and its extracellular location suggest that it might be used by Streptomyces for fighting competitors in its ecological niche, since the enzyme does not hydrolyse the Streptomyces peptidoglycan.	Defined by 7 residues: HIS:A-154ASP:A-161TYR:A-189HIS:A-192ASP:A-194HIS:A-195HIS:A-197 \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 3.4.17.8 (PDB Primary Data) Search M-CSA Motif + EC 3.4.17.8

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