Annotations: 1KT1

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1kt1a1	All alpha proteins	alpha-alpha superhelix	TPR-like	Tetratricopeptide repeat (TPR)	FKBP51, C-terminal domain	Bolivian squirrel monkey (Saimiri boliviensis ) [TaxId: 27679 ],	SCOPe (2.08)
A	d1kt1a2	Alpha and beta proteins (a+b)	FKBP-like	FKBP-like	FKBP immunophilin/proline isomerase	FKBP51, N-terminal domains	Bolivian squirrel monkey (Saimiri boliviensis ) [TaxId: 27679 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Tetratricopeptide repeat (TPR)	8030447	4001344	SCOP2 (2022-06-29)
A	SCOP2 Family	FKBP immunophilin/proline isomerase	8030448	4001062	SCOP2 (2022-06-29)
A	SCOP2 Family	FKBP immunophilin/proline isomerase	8030449	4001062	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	TPR-like	8042826	3001345	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Rotamase-like	8042827	3000622	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Rotamase-like	8042828	3000622	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	TPR_11_8	e1kt1A1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: TPR_11_8	ECOD (1.6)
A	FKBP_C	e1kt1A4	A: a+b two layers	X: FKBP-like	H: FKBP-like	T: FKBP-like	F: FKBP_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.50.40	Alpha Beta	Roll	Chitinase A	domain 3	CATH (4.3.0)
A	1.25.40.10	Mainly Alpha	Alpha Horseshoe	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	Tetratricopeptide repeat domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00515	Tetratricopeptide repeat (TPR_1)	Tetratricopeptide repeat	-	Repeat
A	PF13174	Tetratricopeptide repeat (TPR_6)	Tetratricopeptide repeat	-	Repeat
A	PF00254	FKBP-type peptidyl-prolyl cis-trans isomerase (FKBP_C)	FKBP-type peptidyl-prolyl cis-trans isomerase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	FK506-binding protein FKBP51	isomerase activity catalytic activity, acting on a protein peptidyl-prolyl cis-trans isomerase activity catalytic activity cis-trans isomerase activity protein binding binding heat shock protein binding	biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to bacterium response to external stimulus response to external biotic stimulus response to biotic stimulus organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to bacterium response to external stimulus response to external biotic stimulus response to biotic stimulus organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle nucleoplasm organelle lumen organelle nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR046357	Peptidyl-prolyl cis-trans isomerase domain superfamily	Homologous Superfamily
A	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
A	IPR001179	FKBP-type peptidyl-prolyl cis-trans isomerase domain	Domain
A	IPR019734	Tetratricopeptide repeat	Repeat
A	IPR001440	TPR_1	Unknown

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.