Annotations: 1KK8

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d1kk8b_	All alpha proteins	EF Hand-like	EF-hand	Calmodulin-like	Myosin Essential Chain	(Argopecten irradians ) [TaxId: 31199 ],	SCOPe (2.08)
A	d1kk8a1	All beta proteins	SH3-like barrel	Myosin S1 fragment, N-terminal domain	Myosin S1 fragment, N-terminal domain	Myosin S1 fragment, N-terminal domain	(Argopecten irradians ) [TaxId: 31199 ],	SCOPe (2.08)
A	d1kk8a2	Alpha and beta proteins (a/b)	P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	Motor proteins	Myosin S1, motor domain	(Argopecten irradians ) [TaxId: 31199 ],	SCOPe (2.08)
C	d1kk8c_	All alpha proteins	EF Hand-like	EF-hand	Calmodulin-like	Myosin Regulatory Chain	(Argopecten irradians ) [TaxId: 31199 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	EF-hand	8037349	3001983	SCOP2B (2022-06-29)
A	SCOP2 Family	Myosin s1 fragment N-terminal domain	8030396	4001735	SCOP2 (2022-06-29)
A	SCOP2 Family	Myosin motor domain	8030398	4004054	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Myosin s1 fragment N-terminal domain	8042775	3000319	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	P-loop motor domain	8042777	3002036	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	EF-hand	8037362	3001983	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	F_UNCLASSIFIED	e1kk8B2	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF13499	e1kk8B1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)
A	PF02736	e1kk8A1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: PF02736	ECOD (1.6)
A	PF00612	e1kk8A3	A: alpha bundles	X: Myosin VI lever arm (From Topology)	H: Myosin VI lever arm (From Topology)	T: Myosin VI lever arm	F: PF00612	ECOD (1.6)
A	PF00063	e1kk8A4	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF00063	ECOD (1.6)
C	F_UNCLASSIFIED	e1kk8C3	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
C	PF13499	e1kk8C4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	1.10.238.10	Mainly Alpha	Orthogonal Bundle	Recoverin	domain 1	CATH (4.3.0)
A	2.30.30.360	Mainly Beta	Roll	SH3 type barrels.	Myosin S1 fragment, N-terminal	CATH (utative)
A	1.20.58.530	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (utative)
C	1.10.238.10	Mainly Alpha	Orthogonal Bundle	Recoverin	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B	PF13499	EF-hand domain pair (EF-hand_7)	EF-hand domain pair	-	Domain
A	PF02736	Myosin N-terminal SH3-like domain (Myosin_N)	Myosin N-terminal SH3-like domain	This domain has an SH3-like fold. It is found at the N-terminus of many but not all myosins. The function of this domain is unknown.	Domain
A	PF00063	Myosin head (motor domain) (Myosin_head)	Myosin head (motor domain)	-	Domain
C	PF13499	EF-hand domain pair (EF-hand_7)	EF-hand domain pair	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B	Myosin Regulatory Light Chain, Striated adductor muscle	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding	-	intracellular organelle protein-containing complex intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle cellular anatomical entity actin cytoskeleton non-membrane-bounded organelle myosin complex
A	Myosin Heavy Chain, Striated muscle	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding cytoskeletal protein binding actin binding protein-containing complex binding protein binding actin filament binding calmodulin binding cytoskeletal motor activity	-	intracellular anatomical structure cellular anatomical entity intracellular organelle organelle intracellular non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber myofibril supramolecular polymer supramolecular complex non-membrane-bounded organelle myosin filament protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle organelle intracellular non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber myofibril supramolecular polymer supramolecular complex non-membrane-bounded organelle myosin filament protein-containing complex cytoskeleton actin cytoskeleton myosin complex
C	Myosin Essential Light Chain,Striated adductor muscle	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding	-	intracellular organelle protein-containing complex intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle cellular anatomical entity actin cytoskeleton non-membrane-bounded organelle myosin complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B	IPR018247	EF-Hand 1, calcium-binding site	Binding Site
B	IPR002048	EF-hand domain	Domain
B	IPR011992	EF-hand domain pair	Homologous Superfamily
A	IPR036961	Kinesin motor domain superfamily	Homologous Superfamily
A	IPR014751	DNA repair protein XRCC4-like, C-terminal	Homologous Superfamily
A	IPR001609	Myosin head, motor domain	Domain
A	IPR002928	Myosin tail	Domain
A	IPR004009	Myosin, N-terminal, SH3-like	Domain
A	IPR008989	Myosin S1 fragment, N-terminal	Homologous Superfamily
A	IPR000048	IQ motif, EF-hand binding site	Binding Site
A	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
C	IPR002048	EF-hand domain	Domain
C	IPR011992	EF-hand domain pair	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.