Annotations: 1KFT

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1kfta_	All alpha proteins	SAM domain-like	RuvA domain 2-like	Excinuclease UvrC C-terminal domain	Excinuclease UvrC C-terminal domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Excinuclease UvrC C-terminal domain	8030367	4002380	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Helix-hairpin-helix tandem	8042746	3000163	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	HHH_2_1	e1kftA1	A: alpha arrays	X: HhH/H2TH	H: SAM/DNA-glycosylase	T: SAM domain-like	F: HHH_2_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.150.20	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00633	Helix-hairpin-helix motif (HHH)	Helix-hairpin-helix motif	-	Motif

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Excinuclease ABC subunit C	excinuclease ABC activity DNA endonuclease activity endonuclease activity catalytic activity, acting on DNA nuclease activity hydrolase activity, acting on ester bonds catalytic activity, acting on a nucleic acid hydrolase activity catalytic activity DNA nuclease activity DNA binding binding organic cyclic compound binding nucleic acid binding	cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process nucleotide-excision repair metabolic process cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process nucleotide-excision repair metabolic process macromolecule metabolic process DNA repair response to radiation response to abiotic stimulus SOS response	protein-containing complex catalytic complex excinuclease repair complex endodeoxyribonuclease complex intracellular protein-containing complex endonuclease complex DNA repair complex intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR004791	UvrABC system, subunit C	Family
A	IPR036876	UVR domain superfamily	Homologous Superfamily
A	IPR001162	UvrC, RNAse H endonuclease domain	Domain
A	IPR010994	RuvA domain 2-like	Homologous Superfamily
A	IPR038476	UvrC, RNAse H endonuclease domain superfamily	Homologous Superfamily
A	IPR001943	UVR domain	Domain
A	IPR047296	UvrC/Cho-like, GIY-YIG domain	Domain
A	IPR035901	GIY-YIG endonuclease superfamily	Homologous Superfamily
A	IPR000305	GIY-YIG endonuclease	Domain
A	IPR003583	Helix-hairpin-helix DNA-binding motif, class 1	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.