Annotations: 1JAD

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1jada_	Coiled coil proteins	Antiparallel coiled-coil	C-terminal domain of PLC-beta	C-terminal domain of PLC-beta	C-terminal domain of PLC-beta	turkey (Meleagris gallopavo ) [TaxId: 9103 ],	SCOPe (2.08)
B	d1jadb_	Coiled coil proteins	Antiparallel coiled-coil	C-terminal domain of PLC-beta	C-terminal domain of PLC-beta	C-terminal domain of PLC-beta	turkey (Meleagris gallopavo ) [TaxId: 9103 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	C-terminal domain of PLC-beta	8024467	4003668	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	C-terminal domain of PLC-beta	8036846	3001228	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	C-terminal domain of PLC-beta	8036846	3001228	SCOP2B (2022-06-29)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.1230.10	Mainly Alpha	Up-down Bundle	Phospholipase C Beta	Chain: A	CATH (4.3.0)
B	1.20.1230.10	Mainly Alpha	Up-down Bundle	Phospholipase C Beta	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF08703	PLC-beta C terminal (PLC-beta_C)	PLC-beta C terminal	This domain corresponds to the alpha helical C terminal domain of phospholipase C beta.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	phospholipase C beta	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding phosphoric ester hydrolase activity hydrolase activity, acting on ester bonds phosphoric diester hydrolase activity phospholipase C activity hydrolase activity catalytic activity phosphatidylinositol phospholipase C activity phospholipase activity cation binding ion binding binding calcium ion binding metal ion binding small molecule binding phosphoric ester hydrolase activity hydrolase activity, acting on ester bonds phosphoric diester hydrolase activity phospholipase C activity hydrolase activity catalytic activity phosphatidylinositol phospholipase C activity phospholipase activity lipase activity	lipid catabolic process organic substance metabolic process catabolic process primary metabolic process metabolic process organic substance catabolic process lipid metabolic process cellular response to stimulus regulation of biological process regulation of cellular process response to stimulus signaling biological regulation cellular process lipid catabolic process organic substance metabolic process catabolic process primary metabolic process metabolic process organic substance catabolic process lipid metabolic process cellular response to stimulus regulation of biological process regulation of cellular process response to stimulus signaling biological regulation cellular process signal transduction intracellular signal transduction cell communication	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR028403	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, catalytic domain	Domain
A, B	IPR015359	Phosphoinositide-specific phospholipase C, EF-hand-like domain	Domain
A, B	IPR001192	Phosphoinositide phospholipase C family	Family
A, B	IPR016280	Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta	Family
A, B	IPR042531	Phospholipase C-beta, C-terminal domain superfamily	Homologous Superfamily
A, B	IPR001711	Phospholipase C, phosphatidylinositol-specific, Y domain	Domain
A, B	IPR017946	PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily	Homologous Superfamily
A, B	IPR014815	Phospholipase C-beta, C-terminal domain	Domain
A, B	IPR000008	C2 domain	Domain
A, B	IPR035892	C2 domain superfamily	Homologous Superfamily
A, B	IPR000909	Phosphatidylinositol-specific phospholipase C, X domain	Domain
A, B	IPR046969	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, EF-hand domain	Domain
A, B	IPR011992	EF-hand domain pair	Homologous Superfamily
A, B	IPR037862	PLC-beta, PH domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.