Annotations: 1I8D

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1i8da1	All beta proteins	Reductase/isomerase/elongation factor common domain	Riboflavin synthase domain-like	Riboflavin synthase	Riboflavin synthase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1i8db1	All beta proteins	Reductase/isomerase/elongation factor common domain	Riboflavin synthase domain-like	Riboflavin synthase	Riboflavin synthase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
C	d1i8dc1	All beta proteins	Reductase/isomerase/elongation factor common domain	Riboflavin synthase domain-like	Riboflavin synthase	Riboflavin synthase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Riboflavin synthase	8021395	4003217	SCOP2 (2022-06-29)
A	SCOP2 Family	Riboflavin synthase	8021397	4003217	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Riboflavin synthase domain-like	8033775	3001812	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Riboflavin synthase domain-like	8033777	3001812	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Riboflavin synthase domain-like	8033775	3001812	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Riboflavin synthase domain-like	8033777	3001812	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Riboflavin synthase domain-like	8033775	3001812	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Riboflavin synthase domain-like	8033777	3001812	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00677	e1i8dA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF00677	ECOD (1.6)
B	PF00677	e1i8dB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF00677	ECOD (1.6)
C	PF00677	e1i8dC1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: PF00677	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
B	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
C	2.40.30.20	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00677	Lumazine binding domain (Lum_binding)	Lumazine binding domain	This domain binds to derivatives of lumazine in some proteins. Some proteins have lost the residues involved in binding lumazine.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	RIBOFLAVIN SYNTHASE	riboflavin synthase activity transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups catalytic activity	organonitrogen compound metabolic process water-soluble vitamin biosynthetic process small molecule biosynthetic process cellular biosynthetic process flavin-containing compound metabolic process cellular metabolic process organonitrogen compound biosynthetic process vitamin biosynthetic process riboflavin biosynthetic process vitamin metabolic process organic cyclic compound metabolic process flavin-containing compound biosynthetic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organonitrogen compound metabolic process water-soluble vitamin biosynthetic process small molecule biosynthetic process cellular biosynthetic process flavin-containing compound metabolic process cellular metabolic process organonitrogen compound biosynthetic process vitamin biosynthetic process riboflavin biosynthetic process vitamin metabolic process organic cyclic compound metabolic process flavin-containing compound biosynthetic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process small molecule metabolic process cellular process water-soluble vitamin metabolic process riboflavin metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR017938	Riboflavin synthase-like beta-barrel	Homologous Superfamily
A, B, C	IPR026017	Lumazine-binding domain	Domain
A, B, C	IPR001783	Lumazine-binding protein	Family
A, B, C	IPR023366	ATP synthase subunit alpha, N-terminal domain-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.