Annotations: 1I6P

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1i6pa_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	beta-carbonic anhydrase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	beta-carbonic anhydrase cab	8021319	4000510	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	beta-carbonic anhydrase cab	8033699	3000468	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Pro_CA	e1i6pA1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00484	Carbonic anhydrase (Pro_CA)	Carbonic anhydrase	This family includes carbonic anhydrases as well as a family of non-functional homologues related to YbcF.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	CARBONIC ANHYDRASE	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding carbonate dehydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity identical protein binding protein binding	carbon utilization response to nutrient levels response to stimulus protein-containing complex organization protein homotetramerization cellular component organization cellular component biogenesis cellular component assembly protein complex oligomerization protein tetramerization protein-containing complex assembly protein homooligomerization cellular process cellular component organization or biogenesis	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR001765	Carbonic anhydrase	Family
A	IPR015892	Carbonic anhydrase, prokaryotic-like, conserved site	Conserved Site
A	IPR036874	Carbonic anhydrase superfamily	Homologous Superfamily

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	carbonate dehydratase (beta class) M-CSA #517	Beta-carbonic anhydrases are found in a variety of higher plants, simple eukaryotes, eubacteria and archaea. they catalyse the interconversion of carbon dioxide and bicarbonate. These are zinc-containing metalloenzymes.	Defined by 5 residues: CYS:A-42ASP:A-44ARG:A-46HIS:A-98CYS:A-101 \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 4.2.1.1 (PDB Primary Data) Search M-CSA Motif + EC 4.2.1.1

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