Annotations: 1H3Q

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1h3qa_	Alpha and beta proteins (a+b)	Profilin-like	SNARE-like	Sedlin (SEDL)	Sedlin (SEDL)	MOUSE (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	SNARE-like	8043017	3001113	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF04628	e1h3qA1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: PF04628	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.450.70	Alpha Beta	2-Layer Sandwich	Beta-Lactamase		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF04628	Sedlin, N-terminal conserved region (Sedlin_N)	Sedlin, N-terminal conserved region	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	SEDLIN	transcription factor binding transcription coregulator binding transcription corepressor binding protein binding binding transmembrane transporter binding	developmental process multicellular organism development multicellular organismal process skeletal system development anatomical structure development system development regulation of cellular process cellular biosynthetic process positive regulation of biological process positive regulation of cellular metabolic process positive regulation of macromolecule biosynthetic process positive regulation of metabolic process organic substance metabolic process positive regulation of biosynthetic process developmental process multicellular organism development multicellular organismal process skeletal system development anatomical structure development system development regulation of cellular process cellular biosynthetic process positive regulation of biological process positive regulation of cellular metabolic process positive regulation of macromolecule biosynthetic process positive regulation of metabolic process organic substance metabolic process positive regulation of biosynthetic process organic substance biosynthetic process positive regulation of macromolecule metabolic process positive regulation of cellular process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of cellular biosynthetic process regulation of gene expression biosynthetic process positive regulation of gene expression regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process positive regulation of cellular biosynthetic process vesicle localization establishment of organelle localization cellular localization transport establishment of vesicle localization establishment of localization vesicle targeting vesicle-mediated transport cellular component organization localization organelle localization establishment of localization in cell cellular component organization or biogenesis vesicle tethering vesicle budding from membrane vesicle targeting, to, from or within Golgi vesicle organization cellular component biogenesis cellular component assembly protein-containing complex assembly vesicle coating vesicle targeting, rough ER to cis-Golgi membrane organization protein-containing complex organization intracellular transport endoplasmic reticulum to Golgi vesicle-mediated transport organelle organization COPII-coated vesicle budding COPII vesicle coating Golgi vesicle transport	protein-containing complex intracellular protein-containing complex TRAPP complex vesicle tethering complex membrane-bounded organelle intracellular anatomical structure Golgi apparatus endosome intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle TRAPPII protein complex protein-containing complex intracellular protein-containing complex TRAPP complex vesicle tethering complex membrane-bounded organelle intracellular anatomical structure Golgi apparatus endosome intracellular vesicle cellular anatomical entity intracellular membrane-bounded organelle endomembrane system intracellular organelle TRAPPII protein complex cytoplasmic vesicle organelle cytoplasm vesicle TRAPPIII protein complex perinuclear region of cytoplasm endoplasmic reticulum-Golgi intermediate compartment nucleus membrane-enclosed lumen intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen endoplasmic reticulum

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR011012	Longin-like domain superfamily	Homologous Superfamily
A	IPR006722	Trafficking protein particle complex subunit 2	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.