Annotations: 1GMJ

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1gmja_	Coiled coil proteins	Antiparallel coiled-coil	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	BOVINE (Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
B	d1gmjb_	Coiled coil proteins	Antiparallel coiled-coil	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	BOVINE (Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
C	d1gmjc_	Coiled coil proteins	Antiparallel coiled-coil	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	BOVINE (Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
D	d1gmjd_	Coiled coil proteins	Antiparallel coiled-coil	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	F1 ATPase inhibitor, IF1, C-terminal domain	BOVINE (Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.5.500	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)
B	1.20.5.500	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)
C	1.20.5.500	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)
D	1.20.5.500	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF04568	Mitochondrial ATPase inhibitor, IATP (IATP)	Mitochondrial ATPase inhibitor, IATP	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	ATPASE INHIBITOR	identical protein binding protein binding binding protein homodimerization activity protein dimerization activity angiostatin binding calmodulin binding molecular function inhibitor activity molecular function regulator activity ATPase inhibitor activity ATPase regulator activity structural molecule activity ATPase binding enzyme binding	developmental process multicellular organismal process cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation immune system process cell differentiation anatomical structure development homeostasis of number of cells cellular process developmental process multicellular organismal process cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation immune system process cell differentiation anatomical structure development homeostasis of number of cells cellular process myeloid cell homeostasis erythrocyte homeostasis protein-containing complex organization protein homotetramerization cellular component organization cellular component biogenesis cellular component assembly protein complex oligomerization protein tetramerization protein-containing complex assembly protein homooligomerization cellular component organization or biogenesis pigment metabolic process heme metabolic process porphyrin-containing compound biosynthetic process organonitrogen compound metabolic process tetrapyrrole metabolic process heme biosynthetic process organonitrogen compound biosynthetic process pigment biosynthetic process organic cyclic compound metabolic process organic substance metabolic process tetrapyrrole biosynthetic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process porphyrin-containing compound metabolic process negative regulation of cell population proliferation regulation of biological process cell population proliferation regulation of cellular process endothelial cell proliferation biological regulation negative regulation of biological process negative regulation of endothelial cell proliferation regulation of endothelial cell proliferation regulation of cell population proliferation negative regulation of cellular process regulation of epithelial cell proliferation epithelial cell proliferation negative regulation of epithelial cell proliferation negative regulation of hydrolase activity regulation of molecular function regulation of catalytic activity regulation of hydrolase activity negative regulation of molecular function negative regulation of catalytic activity	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle cell surface protein-containing complex ATPase complex mitochondrial membrane organelle inner membrane membrane protein complex membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle cell surface protein-containing complex ATPase complex mitochondrial membrane organelle inner membrane membrane protein complex organelle envelope proton-transporting two-sector ATPase complex mitochondrial protein-containing complex catalytic complex membrane proton-transporting ATP synthase complex mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex inner mitochondrial membrane protein complex mitochondrial envelope organelle membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR007648	Mitochondrial ATPase inhibitor	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.