Annotations: 1F8X

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1f8xa_	Alpha and beta proteins (a/b)	Flavodoxin-like	N-(deoxy)ribosyltransferase-like	N-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase	(Lactobacillus leichmannii ) [TaxId: 28039 ],	SCOPe (2.08)
B	d1f8xb_	Alpha and beta proteins (a/b)	Flavodoxin-like	N-(deoxy)ribosyltransferase-like	N-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase	(Lactobacillus leichmannii ) [TaxId: 28039 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	N-(deoxy)ribosyltransferase-like	8044137	3001392	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	N-(deoxy)ribosyltransferase-like	8044137	3001392	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05014	e1f8xA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: N-deoxyribosyltransferase (From Topology)	T: N-deoxyribosyltransferase	F: PF05014	ECOD (1.6)
B	PF05014	e1f8xB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: N-deoxyribosyltransferase (From Topology)	T: N-deoxyribosyltransferase	F: PF05014	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.450	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
B	3.40.50.450	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF05014	Nucleoside 2-deoxyribosyltransferase (Nuc_deoxyrib_tr)	Nucleoside 2-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase EC:2.4.2.6 catalyses the cleavage of the glycosidic bonds of 2`-deoxyribonucleosides [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE	nucleoside deoxyribosyltransferase activity pentosyltransferase activity glycosyltransferase activity transferase activity catalytic activity	nucleotide biosynthetic process nucleotide salvage nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process organic substance biosynthetic process phosphate-containing compound metabolic process small molecule metabolic process cellular metabolic compound salvage phosphorus metabolic process nucleoside phosphate metabolic process cellular metabolic process primary metabolic process nucleobase-containing compound biosynthetic process nucleotide biosynthetic process nucleotide salvage nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process organic substance biosynthetic process phosphate-containing compound metabolic process small molecule metabolic process cellular metabolic compound salvage phosphorus metabolic process nucleoside phosphate metabolic process cellular metabolic process primary metabolic process nucleobase-containing compound biosynthetic process nucleotide metabolic process organic cyclic compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process organic cyclic compound biosynthetic process nucleoside phosphate biosynthetic process metabolic process cellular process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR007710	Nucleoside 2-deoxyribosyltransferase	Family

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	nucleoside deoxyribosyltransferase M-CSA #554	Nucleoside 2'-deoxyribosyltransferase catalyses cleavage of the 2'-deoxyribosyl-nucleoside glycosidic bond through the formation of a covalent deoxyribosyl-enzyme intermediate. The enzyme is found in various Lactobacilli species where it participates in nucleoside recycling. There is considerable interest for nucleoside 2'-deoxyribosyltransferase to be used as an industrial biocatalyst in creating natural and non-natural nucleosides.	Defined by 4 residues: TYR:A-7ASP:A-72ASP:A-92GLU:A-98 \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 2.4.2.6 (PDB Primary Data) Search M-CSA Motif + EC 2.4.2.6

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