Annotations: 1ES6

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1es6a1	All beta proteins	EV matrix protein	EV matrix protein	EV matrix protein	EV matrix protein	(Ebola virus sp. ) [TaxId: 205488 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	VP40_C	e1es6A2	A: beta barrels	X: EV matrix protein (From Homology)	H: EV matrix protein	T: EV matrix protein	F: VP40_C	ECOD (1.6)
A	VP40_N	e1es6A1	A: beta barrels	X: EV matrix protein (From Homology)	H: EV matrix protein	T: EV matrix protein	F: VP40_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.20.20	Mainly Beta	Distorted Sandwich	Topoisomerase I	domain 3	CATH (4.3.0)
A	2.60.510.10	Mainly Beta	Sandwich	EV matrix protein fold	EV matrix protein	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF07447	Matrix protein VP40 (VP40)	Matrix protein VP40	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	MATRIX PROTEIN VP40	structural constituent of virion structural molecule activity RNA binding binding organic cyclic compound binding nucleic acid binding	virion assembly viral process viral budding viral budding via host ESCRT complex viral life cycle	host cellular component host cell endomembrane system host cell part host cell membrane cellular anatomical entity membrane virion component virion membrane extracellular region host intracellular membrane-bounded organelle host intracellular part host cell cytoplasm part host cell late endosome membrane host intracellular organelle host cellular component host cell endomembrane system host cell part host cell membrane cellular anatomical entity membrane virion component virion membrane extracellular region host intracellular membrane-bounded organelle host intracellular part host cell cytoplasm part host cell late endosome membrane host intracellular organelle host cell cytoplasm host cell endosome membrane host cell late endosome host cell endosome host intracellular region host cell plasma membrane protein-containing complex ribonucleoprotein complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR043079	EV matrix protein, N-terminal	Homologous Superfamily
A	IPR008986	EV matrix protein	Family
A	IPR038057	EV matrix domain superfamily	Homologous Superfamily
A	IPR035092	EV matrix protein, C-terminal	Homologous Superfamily

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM				Matrix protein VP40

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.