Annotations: 1EFP

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
D	d1efpd_	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Adenine nucleotide alpha hydrolases-like	ETFP subunits	Small, beta subunit of electron transfer flavoprotein ETFP	(Paracoccus denitrificans ) [TaxId: 266 ],	SCOPe (2.08)
B	d1efpb_	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Adenine nucleotide alpha hydrolases-like	ETFP subunits	Small, beta subunit of electron transfer flavoprotein ETFP	(Paracoccus denitrificans ) [TaxId: 266 ],	SCOPe (2.08)
C	d1efpc1	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Adenine nucleotide alpha hydrolases-like	ETFP subunits	Large, alpha subunit of electron transfer flavoprotein ETFP, N-terminal domain	(Paracoccus denitrificans ) [TaxId: 266 ],	SCOPe (2.08)
C	d1efpc2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	C-terminal domain of the electron transfer flavoprotein alpha subunit	C-terminal domain of the electron transfer flavoprotein alpha subunit	(Paracoccus denitrificans ) [TaxId: 266 ],	SCOPe (2.08)
A	d1efpa1	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Adenine nucleotide alpha hydrolases-like	ETFP subunits	Large, alpha subunit of electron transfer flavoprotein ETFP, N-terminal domain	(Paracoccus denitrificans ) [TaxId: 266 ],	SCOPe (2.08)
A	d1efpa2	Alpha and beta proteins (a/b)	DHS-like NAD/FAD-binding domain	DHS-like NAD/FAD-binding domain	C-terminal domain of the electron transfer flavoprotein alpha subunit	C-terminal domain of the electron transfer flavoprotein alpha subunit	(Paracoccus denitrificans ) [TaxId: 266 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
D	SCOP2B Superfamily	Adenine nucleotide alpha hydrolases-like	8044218	3001593	SCOP2B (2022-06-29)
B	SCOP2 Family	ETFP subunits	8031840	4003848	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Adenine nucleotide alpha hydrolases-like	8044218	3001593	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	Adenine nucleotide alpha hydrolases-like	8044217	3001593	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DHS-like NAD/FAD-binding domain	8044244	3001728	SCOP2B (2022-06-29)
A	SCOP2 Family	ETFP subunits	8031839	4003848	SCOP2 (2022-06-29)
A	SCOP2 Family	C-terminal domain of the electron transfer flavoprotein alpha subunit	8031866	4003888	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Adenine nucleotide alpha hydrolases-like	8044217	3001593	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	DHS-like NAD/FAD-binding domain	8044244	3001728	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	PF01012	e1efpD1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: PF01012	ECOD (1.6)
B	PF01012	e1efpB1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: PF01012	ECOD (1.6)
C	PF00766	e1efpC1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: PF00766	ECOD (1.6)
C	PF01012	e1efpC2	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: PF01012	ECOD (1.6)
A	PF00766	e1efpA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: DHS-like NAD/FAD-binding domain	F: PF00766	ECOD (1.6)
A	PF01012	e1efpA2	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: PF01012	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
D	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)
B	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)
C	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
C	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)
A	3.40.50.1220	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	TPP-binding domain	CATH (4.3.0)
A	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B, D	PF01012	Electron transfer flavoprotein domain (ETF)	Electron transfer flavoprotein domain	This family includes the homologous domain shared between the alpha and beta subunits of the electron transfer flavoprotein [1].	Domain
A, C	PF00766	Electron transfer flavoprotein FAD-binding domain (ETF_alpha)	Electron transfer flavoprotein FAD-binding domain	This domain found at the C-terminus of electron transfer flavoprotein alpha chain and binds to FAD [1]. The fold consists of a five-stranded parallel beta sheet as the core of the domain, flanked by alternating helices. A small part of this domain i ...	This domain found at the C-terminus of electron transfer flavoprotein alpha chain and binds to FAD [1]. The fold consists of a five-stranded parallel beta sheet as the core of the domain, flanked by alternating helices. A small part of this domain is donated by the beta chain [1].	Domain
A, C	PF01012	Electron transfer flavoprotein domain (ETF)	Electron transfer flavoprotein domain	This family includes the homologous domain shared between the alpha and beta subunits of the electron transfer flavoprotein [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B, D	PROTEIN (ELECTRON TRANSFER FLAVOPROTEIN)	electron transfer activity	-	-
A, C	PROTEIN (ELECTRON TRANSFER FLAVOPROTEIN)	electron transfer activity flavin adenine dinucleotide binding binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B, D	IPR014730	Electron transfer flavoprotein, alpha/beta-subunit, N-terminal	Domain
B, D	IPR033948	Electron transfer flavoprotein, beta subunit, N-terminal	Domain
B, D	IPR000049	Electron transfer flavoprotein, beta-subunit, conserved site	Conserved Site
B, D	IPR012255	Electron transfer flavoprotein, beta subunit	Family
B, D	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	Homologous Superfamily
A, C	IPR014730	Electron transfer flavoprotein, alpha/beta-subunit, N-terminal	Domain
A, C	IPR001308	Electron transfer flavoprotein alpha subunit/FixB	Family
A, C	IPR014731	Electron transfer flavoprotein, alpha subunit, C-terminal	Domain
A, C	IPR029035	DHS-like NAD/FAD-binding domain superfamily	Homologous Superfamily
A, C	IPR018206	Electron transfer flavoprotein subunit alpha, conserved site	Conserved Site
A, C	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	Homologous Superfamily
A, C	IPR033947	Electron transfer flavoprotein, alpha subunit, N-terminal	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.