1E7P

QUINOL:FUMARATE REDUCTASE FROM WOLINELLA SUCCINOGENES

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1e7pa1	All alpha proteins	Spectrin repeat-like	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
A	d1e7pa2	Alpha and beta proteins (a/b)	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
A	d1e7pa3	Alpha and beta proteins (a+b)	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
D	d1e7pd1	All alpha proteins	Spectrin repeat-like	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
D	d1e7pd2	Alpha and beta proteins (a/b)	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
D	d1e7pd3	Alpha and beta proteins (a+b)	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
G	d1e7pg1	All alpha proteins	Spectrin repeat-like	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
G	d1e7pg2	Alpha and beta proteins (a/b)	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
G	d1e7pg3	Alpha and beta proteins (a+b)	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
J	d1e7pj1	All alpha proteins	Spectrin repeat-like	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
J	d1e7pj2	Alpha and beta proteins (a/b)	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
J	d1e7pj3	Alpha and beta proteins (a+b)	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
B	d1e7pb1	All alpha proteins	Globin-like	alpha-helical ferredoxin	Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
B	d1e7pb2	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	2Fe-2S ferredoxin-like	2Fe-2S ferredoxin domains from multidomain proteins	Fumarate reductase iron-sulfur protein, N-terminal domain	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
E	d1e7pe1	All alpha proteins	Globin-like	alpha-helical ferredoxin	Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
E	d1e7pe2	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	2Fe-2S ferredoxin-like	2Fe-2S ferredoxin domains from multidomain proteins	Fumarate reductase iron-sulfur protein, N-terminal domain	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
H	d1e7ph1	All alpha proteins	Globin-like	alpha-helical ferredoxin	Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
H	d1e7ph2	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	2Fe-2S ferredoxin-like	2Fe-2S ferredoxin domains from multidomain proteins	Fumarate reductase iron-sulfur protein, N-terminal domain	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
K	d1e7pk1	All alpha proteins	Globin-like	alpha-helical ferredoxin	Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain	Fumarate reductase	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
K	d1e7pk2	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	2Fe-2S ferredoxin-like	2Fe-2S ferredoxin domains from multidomain proteins	Fumarate reductase iron-sulfur protein, N-terminal domain	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
C	d1e7pc_	Membrane and cell surface proteins and peptides	Heme-binding four-helical bundle	Fumarate reductase respiratory complex transmembrane subunits	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
F	d1e7pf_	Membrane and cell surface proteins and peptides	Heme-binding four-helical bundle	Fumarate reductase respiratory complex transmembrane subunits	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
I	d1e7pi_	Membrane and cell surface proteins and peptides	Heme-binding four-helical bundle	Fumarate reductase respiratory complex transmembrane subunits	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)
L	d1e7pl_	Membrane and cell surface proteins and peptides	Heme-binding four-helical bundle	Fumarate reductase respiratory complex transmembrane subunits	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Fumarate reductase respiratory complex cytochrome b subunit, FrdC	Vibrio succinogenes (Wolinella succinogenes ) [TaxId: 844 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Succinate dehydrogenase/fumarate reductase domain-like	8056073	3000054	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	L-aspartate oxidase C-terminal domain-like	8056074	3000021	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Succinate dehydrogenase/fumarate reductase domain-like	8056073	3000054	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	L-aspartate oxidase C-terminal domain-like	8056074	3000021	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Succinate dehydrogenase/fumarate reductase domain-like	8056073	3000054	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	L-aspartate oxidase C-terminal domain-like	8056074	3000021	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	L-aspartate oxidase C-terminal domain-like	8056074	3000021	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Succinate dehydrogenase/fumarate reductase domain-like	8056073	3000054	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	alpha-helical ferredoxin	8089676	3000026	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	2Fe-2S ferredoxin-like	8089674	3000113	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	alpha-helical ferredoxin	8089676	3000026	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	2Fe-2S ferredoxin-like	8089674	3000113	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	alpha-helical ferredoxin	8089676	3000026	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	2Fe-2S ferredoxin-like	8089674	3000113	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	alpha-helical ferredoxin	8089676	3000026	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	2Fe-2S ferredoxin-like	8089674	3000113	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Fumarate reductase respiratory complex transmembrane subunits	8038469	3000518	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Fumarate reductase respiratory complex transmembrane subunits	8038469	3000518	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Fumarate reductase respiratory complex transmembrane subunits	8038469	3000518	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Fumarate reductase respiratory complex transmembrane subunits	8038469	3000518	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Succ_DH_flav_C	e1e7pA1	A: alpha bundles	X: Spectrin repeat-like	H: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	F: Succ_DH_flav_C	ECOD (1.6)
A	FAD_binding_2	e1e7pA2	A: a+b complex topology	X: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	H: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	F: FAD_binding_2	ECOD (1.6)
A	FAD_binding_3_1st	e1e7pA3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: FAD_binding_3_1st	ECOD (1.6)
D	Succ_DH_flav_C	e1e7pD1	A: alpha bundles	X: Spectrin repeat-like	H: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	F: Succ_DH_flav_C	ECOD (1.6)
D	FAD_binding_2	e1e7pD2	A: a+b complex topology	X: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	H: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	F: FAD_binding_2	ECOD (1.6)
D	FAD_binding_3_1st	e1e7pD3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: FAD_binding_3_1st	ECOD (1.6)
G	Succ_DH_flav_C	e1e7pG1	A: alpha bundles	X: Spectrin repeat-like	H: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	F: Succ_DH_flav_C	ECOD (1.6)
G	FAD_binding_2	e1e7pG2	A: a+b complex topology	X: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	H: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	F: FAD_binding_2	ECOD (1.6)
G	FAD_binding_3_1st	e1e7pG3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: FAD_binding_3_1st	ECOD (1.6)
J	Succ_DH_flav_C	e1e7pJ1	A: alpha bundles	X: Spectrin repeat-like	H: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	F: Succ_DH_flav_C	ECOD (1.6)
J	FAD_binding_2	e1e7pJ2	A: a+b complex topology	X: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	H: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)	T: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	F: FAD_binding_2	ECOD (1.6)
J	FAD_binding_3_1st	e1e7pJ3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: FAD_binding_3_1st	ECOD (1.6)
B	Fer4_8	e1e7pB1	A: alpha arrays	X: alpha-helical ferredoxin-like	H: alpha-helical ferredoxin (From Topology)	T: alpha-helical ferredoxin	F: Fer4_8	ECOD (1.6)
B	Fer2_3	e1e7pB2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: Fer2_3	ECOD (1.6)
E	Fer4_8	e1e7pE1	A: alpha arrays	X: alpha-helical ferredoxin-like	H: alpha-helical ferredoxin (From Topology)	T: alpha-helical ferredoxin	F: Fer4_8	ECOD (1.6)
E	Fer2_3	e1e7pE2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: Fer2_3	ECOD (1.6)
H	Fer4_8	e1e7pH1	A: alpha arrays	X: alpha-helical ferredoxin-like	H: alpha-helical ferredoxin (From Topology)	T: alpha-helical ferredoxin	F: Fer4_8	ECOD (1.6)
H	Fer2_3	e1e7pH2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: Fer2_3	ECOD (1.6)
K	Fer4_8	e1e7pK1	A: alpha arrays	X: alpha-helical ferredoxin-like	H: alpha-helical ferredoxin (From Topology)	T: alpha-helical ferredoxin	F: Fer4_8	ECOD (1.6)
K	Fer2_3	e1e7pK2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: Fer2_3	ECOD (1.6)
C	Sdh_cyt	e1e7pC1	A: alpha bundles	X: Transmembrane heme-binding four-helical bundle (From Homology)	H: Transmembrane heme-binding four-helical bundle	T: Fumarate reductase respiratory complex transmembrane subunits	F: Sdh_cyt	ECOD (1.6)
F	Sdh_cyt	e1e7pF1	A: alpha bundles	X: Transmembrane heme-binding four-helical bundle (From Homology)	H: Transmembrane heme-binding four-helical bundle	T: Fumarate reductase respiratory complex transmembrane subunits	F: Sdh_cyt	ECOD (1.6)
I	Sdh_cyt	e1e7pI1	A: alpha bundles	X: Transmembrane heme-binding four-helical bundle (From Homology)	H: Transmembrane heme-binding four-helical bundle	T: Fumarate reductase respiratory complex transmembrane subunits	F: Sdh_cyt	ECOD (1.6)
L	Sdh_cyt	e1e7pL1	A: alpha bundles	X: Transmembrane heme-binding four-helical bundle (From Homology)	H: Transmembrane heme-binding four-helical bundle	T: Fumarate reductase respiratory complex transmembrane subunits	F: Sdh_cyt	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.50.50.60	Alpha Beta	3-Layer(bba) Sandwich	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	CATH (4.3.0)
A	3.90.700.10	Alpha Beta	Alpha-Beta Complex	Flavocytochrome C3	Chain A, domain 1	CATH (4.3.0)
A	1.20.58.100	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
A	3.10.20.820	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)
D	3.50.50.60	Alpha Beta	3-Layer(bba) Sandwich	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	CATH (4.3.0)
D	3.90.700.10	Alpha Beta	Alpha-Beta Complex	Flavocytochrome C3	Chain A, domain 1	CATH (4.3.0)
D	1.20.58.100	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
D	3.10.20.820	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)
G	3.50.50.60	Alpha Beta	3-Layer(bba) Sandwich	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	CATH (4.3.0)
G	3.90.700.10	Alpha Beta	Alpha-Beta Complex	Flavocytochrome C3	Chain A, domain 1	CATH (4.3.0)
G	1.20.58.100	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
G	3.10.20.820	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)
J	3.50.50.60	Alpha Beta	3-Layer(bba) Sandwich	FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	CATH (4.3.0)
J	3.90.700.10	Alpha Beta	Alpha-Beta Complex	Flavocytochrome C3	Chain A, domain 1	CATH (4.3.0)
J	1.20.58.100	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)
J	3.10.20.820	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)
B	3.10.20.30	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Beta-grasp domain	CATH (4.3.0)
B	1.10.1060.10	Mainly Alpha	Orthogonal Bundle	Fumarate Reductase Iron-sulfur Protein	Chain B, domain 2	CATH (4.3.0)
E	3.10.20.30	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Beta-grasp domain	CATH (4.3.0)
E	1.10.1060.10	Mainly Alpha	Orthogonal Bundle	Fumarate Reductase Iron-sulfur Protein	Chain B, domain 2	CATH (4.3.0)
H	3.10.20.30	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Beta-grasp domain	CATH (4.3.0)
H	1.10.1060.10	Mainly Alpha	Orthogonal Bundle	Fumarate Reductase Iron-sulfur Protein	Chain B, domain 2	CATH (4.3.0)
K	3.10.20.30	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Beta-grasp domain	CATH (4.3.0)
K	1.10.1060.10	Mainly Alpha	Orthogonal Bundle	Fumarate Reductase Iron-sulfur Protein	Chain B, domain 2	CATH (4.3.0)
C	1.20.1300.10	Mainly Alpha	Up-down Bundle	3 helical TM bundles of succinate and fumarate reductases	Fumarate reductase/succinate dehydrogenase, transmembrane subunit	CATH (4.3.0)
F	1.20.1300.10	Mainly Alpha	Up-down Bundle	3 helical TM bundles of succinate and fumarate reductases	Fumarate reductase/succinate dehydrogenase, transmembrane subunit	CATH (4.3.0)
I	1.20.1300.10	Mainly Alpha	Up-down Bundle	3 helical TM bundles of succinate and fumarate reductases	Fumarate reductase/succinate dehydrogenase, transmembrane subunit	CATH (4.3.0)
L	1.20.1300.10	Mainly Alpha	Up-down Bundle	3 helical TM bundles of succinate and fumarate reductases	Fumarate reductase/succinate dehydrogenase, transmembrane subunit	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, D, G, J	PF02910	Fumarate reductase flavoprotein C-term (Succ_DH_flav_C)	Fumarate reductase flavoprotein C-term	This family contains fumarate reductases, succinate dehydrogenases and L-aspartate oxidases.	Domain
A, D, G, J	PF00890	FAD binding domain (FAD_binding_2)	FAD binding domain	-	Family
B, E, H, K	PF13183	4Fe-4S dicluster domain (Fer4_8)	4Fe-4S dicluster domain	Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contai ...	Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.	Domain
B, E, H, K	PF13085	2Fe-2S iron-sulfur cluster binding domain (Fer2_3)	2Fe-2S iron-sulfur cluster binding domain	The 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which abeta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated.	Domain
C, F, I, L	PF01127	Succinate dehydrogenase/Fumarate reductase transmembrane subunit (Sdh_cyt)	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D, G, J	Fumarate reductase flavoprotein subunit	flavin adenine dinucleotide binding binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding small molecule binding oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors catalytic activity	cellular metabolic process electron transport chain metabolic process cellular process generation of precursor metabolites and energy	membrane respirasome cellular anatomical entity cell periphery plasma membrane
B, E, H, K	Fumarate reductase iron-sulfur subunit	iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding binding metal cluster binding small molecule binding 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding electron transfer activity cation binding ion binding metal ion binding	aerobic respiration cellular respiration tricarboxylic acid cycle energy derivation by oxidation of organic compounds cellular metabolic process metabolic process cellular process primary metabolic process generation of precursor metabolites and energy	membrane respirasome cellular anatomical entity cell periphery plasma membrane
C, F, I, L	Fumarate reductase cytochrome b subunit	cation binding ion binding binding metal ion binding small molecule binding oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors catalytic activity	aerobic respiration cellular respiration tricarboxylic acid cycle energy derivation by oxidation of organic compounds cellular metabolic process metabolic process cellular process primary metabolic process generation of precursor metabolites and energy	cell periphery plasma membrane membrane cellular anatomical entity respirasome

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, D, G, J	IPR015939	Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal	Domain
A, D, G, J	IPR003952	Fumarate reductase/succinate dehydrogenase, FAD-binding site	Binding Site
A, D, G, J	IPR037099	Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily	Homologous Superfamily
A, D, G, J	IPR036188	FAD/NAD(P)-binding domain superfamily	Homologous Superfamily
A, D, G, J	IPR003953	FAD-dependent oxidoreductase 2, FAD binding domain	Domain
A, D, G, J	IPR030664	FAD-dependent oxidoreductase SdhA/FrdA/AprA	Family
A, D, G, J	IPR027477	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily	Homologous Superfamily
A, D, G, J	IPR014006	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	Family
B, E, H, K	IPR025192	Succinate dehydogenase/fumarate reductase N-terminal	Domain
B, E, H, K	IPR036010	2Fe-2S ferredoxin-like superfamily	Homologous Superfamily
B, E, H, K	IPR001041	2Fe-2S ferredoxin-type iron-sulfur binding domain	Domain
B, E, H, K	IPR006058	2Fe-2S ferredoxin, iron-sulphur binding site	Binding Site
B, E, H, K	IPR004489	Succinate dehydrogenase/fumarate reductase iron-sulphur protein	Family
B, E, H, K	IPR009051	Alpha-helical ferredoxin	Homologous Superfamily
B, E, H, K	IPR017900	4Fe-4S ferredoxin, iron-sulphur binding, conserved site	Conserved Site
B, E, H, K	IPR017896	4Fe-4S ferredoxin-type, iron-sulphur binding domain	Domain
B, E, H, K	IPR012675	Beta-grasp domain superfamily	Homologous Superfamily
C, F, I, L	IPR034804	Fumarate reductase/succinate dehydrogenase, transmembrane subunit	Homologous Superfamily
C, F, I, L	IPR000701	Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit	Family
C, F, I, L	IPR004224	Fumarate reductase type B, transmembrane subunit	Family