Annotations: 1DD4

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1dd4a1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
A	d1dd4a2	Alpha and beta proteins (a+b)	ClpS-like	ClpS-like	Ribosomal protein L7/12, C-terminal domain	Ribosomal protein L7/12, C-terminal domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
B	d1dd4b1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
B	d1dd4b2	Alpha and beta proteins (a+b)	ClpS-like	ClpS-like	Ribosomal protein L7/12, C-terminal domain	Ribosomal protein L7/12, C-terminal domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
C	d1dd4c_	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
D	d1dd4d_	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	ClpS-like	8035078	3000936	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Ribosomal protein L7/12 oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Ribosomal protein L7/12 oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ClpS-like	8035078	3000936	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Ribosomal protein L7/12 oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Ribosomal protein L7/12 oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ribosomal_L12_N	e1dd4A3	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N	ECOD (1.6)
A	Ribosomal_L12	e1dd4A2	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: Ribosomal_L12	ECOD (1.6)
B	Ribosomal_L12_N	e1dd4B3	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N	ECOD (1.6)
B	Ribosomal_L12	e1dd4B2	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: Ribosomal_L12	ECOD (1.6)
C	Ribosomal_L12_N_2	e1dd4C1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N_2	ECOD (1.6)
D	Ribosomal_L12_N	e1dd4D1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.5.710	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)
A	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
B	1.20.5.710	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)
B	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
D	1.20.5.710	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single helix bin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF16320	Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)	Ribosomal protein L7/L12 dimerisation domain	This is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1].	Domain
A, B	PF00542	Ribosomal protein L7/L12 C-terminal domain (Ribosomal_L12)	Ribosomal protein L7/L12 C-terminal domain	-	Domain
C, D	PF16320	Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)	Ribosomal protein L7/L12 dimerisation domain	This is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	50S RIBOSOMAL PROTEIN L7/L12	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit non-membrane-bounded organelle
C, D	50S RIBOSOMAL PROTEIN L7/L12	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process organonitrogen compound biosynthetic process primary metabolic process translation gene expression macromolecule biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process	protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit protein-containing complex intracellular anatomical structure cellular anatomical entity intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex intracellular non-membrane-bounded organelle ribosome cytoplasm cytosol large ribosomal subunit non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR008932	Large ribosomal subunit protein bL12, oligomerization	Domain
A, B	IPR013823	Large ribosomal subunit protein bL12, C-terminal	Domain
A, B	IPR036235	Large ribosomal subunit protein bL12, oligomerization domain superfamily	Homologous Superfamily
A, B	IPR014719	Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like	Homologous Superfamily
A, B	IPR000206	Large ribosomal subunit protein bL12	Family
C, D	IPR008932	Large ribosomal subunit protein bL12, oligomerization	Domain
C, D	IPR013823	Large ribosomal subunit protein bL12, C-terminal	Domain
C, D	IPR036235	Large ribosomal subunit protein bL12, oligomerization domain superfamily	Homologous Superfamily
C, D	IPR014719	Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like	Homologous Superfamily
C, D	IPR000206	Large ribosomal subunit protein bL12	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.