1CMR

NMR SOLUTION STRUCTURE OF A CHIMERIC PROTEIN, DESIGNED BY TRANSFERRING A FUNCTIONAL SNAKE BETA-HAIRPIN INTO A SCORPION ALPHA/BETA SCAFFOLD (PH 3.5, 20C), NMR, 18 STRUCTURES

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1cmra_ Small proteins Knottins (small inhibitors, toxins, lectins) Scorpion toxin-like Short-chain scorpion toxins Charybdotoxin ( ) [TaxId: ], (Leiurus hebraeus ) [TaxId: 6884 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF00451e1cmrA1 A: few secondary structure elementsX: omega toxin-likeH: omega toxin-relatedT: Scorpion toxin-likeF: PF00451ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00451Scorpion short toxin, BmKK2 (Toxin_2)Scorpion short toxin, BmKK2Members of this family, which are found in various scorpion toxins, confer potassium channel blocking activity [1].Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
CHARYBDOTOXIN, ALPHA CHIMERA

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR036574Knottin, scorpion toxin-like superfamilyHomologous Superfamily
IPR001947Scorpion short chain toxin, potassium channel inhibitorFamily