Annotations: 1CII

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1ciia1	Membrane and cell surface proteins and peptides	Toxins' membrane translocation domains	Colicin	Colicin	Colicin Ia	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
A	d1ciia2	Coiled coil proteins	Antiparallel coiled-coil	Colicin Ia, N-terminal domain	Colicin Ia, N-terminal domain	Colicin Ia, N-terminal domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Colicin Ia N-terminal domain	8027279	4003863	SCOP2 (2022-06-29)
A	SCOP2 Family	Colicin	8025260	4002963	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Colicin Ia N-terminal domain	8039658	3001686	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Colicin	8037639	3001946	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01024	e1ciiA1	A: alpha arrays	X: Toxins' membrane translocation domains	H: Colicin (From Topology)	T: Colicin	F: PF01024	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.250.10	Mainly Alpha	Up-down Bundle	Colicin Ia	domain 1	CATH (4.3.0)
A	3.30.305.10	Alpha Beta	2-Layer Sandwich	Colicin Ia	domain 2	CATH (4.3.0)
A	1.10.490.30	Mainly Alpha	Orthogonal Bundle	Globin-like	Colicin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01024	Colicin pore forming domain (Colicin)	Colicin pore forming domain	-	Domain
A	PF11504	Colicin Ia (Colicin_Ia)	Colicin Ia	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	COLICIN IA	pore-forming activity	biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response response to external stimulus defense response to Gram-negative bacterium response to biotic stimulus defense response to bacterium defense response to other organism response to stress response to bacterium response to external biotic stimulus cellular process disruption of cell in another organism biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response response to external stimulus defense response to Gram-negative bacterium response to biotic stimulus defense response to bacterium defense response to other organism response to stress response to bacterium response to external biotic stimulus cellular process disruption of cell in another organism disruption of anatomical structure in another organism killing of cells of another organism cell killing	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR014739	Channel forming colicin, N-terminal domain superfamily	Homologous Superfamily
A	IPR038283	Channel forming colicin, C-terminal domain superfamily	Homologous Superfamily
A	IPR014740	Channel forming colicin, central receptor recognition	Domain
A	IPR000293	Channel forming colicin, C-terminal cytotoxic	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.