Annotations: 1C4P

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1c4pa_	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Staphylokinase/streptokinase	Staphylokinase/streptokinase	Streptokinase	(Streptococcus dysgalactiae subsp. equisimilis ) [TaxId: 119602 ],	SCOPe (2.08)
B	d1c4pb_	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Staphylokinase/streptokinase	Staphylokinase/streptokinase	Streptokinase	(Streptococcus dysgalactiae subsp. equisimilis ) [TaxId: 119602 ],	SCOPe (2.08)
C	d1c4pc_	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Staphylokinase/streptokinase	Staphylokinase/streptokinase	Streptokinase	(Streptococcus dysgalactiae subsp. equisimilis ) [TaxId: 119602 ],	SCOPe (2.08)
D	d1c4pd_	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	Staphylokinase/streptokinase	Staphylokinase/streptokinase	Streptokinase	(Streptococcus dysgalactiae subsp. equisimilis ) [TaxId: 119602 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Staphylokinase/streptokinase	8034552	3000371	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Staphylokinase/streptokinase	8034552	3000371	SCOP2B (2022-06-29)
C	SCOP2 Family	Staphylokinase/streptokinase	8022172	4000987	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	Staphylokinase/streptokinase	8034552	3000371	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Staphylokinase/streptokinase	8034552	3000371	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02821	e1c4pA1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: PF02821	ECOD (1.6)
B	PF02821	e1c4pB1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: PF02821	ECOD (1.6)
C	PF02821	e1c4pC1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: PF02821	ECOD (1.6)
D	PF02821	e1c4pD1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: PF02821	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.20.180	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)
B	3.10.20.180	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)
C	3.10.20.180	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)
D	3.10.20.180	Alpha Beta	Roll	Ubiquitin-like (UB roll)		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02821	Staphylokinase/Streptokinase family (Staphylokinase)	Staphylokinase/Streptokinase family	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	PROTEIN (STREPTOKINASE)	-	zymogen activation organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process biosynthetic process proteolysis organic substance biosynthetic process protein processing metabolic process zymogen activation organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process biosynthetic process proteolysis organic substance biosynthetic process protein processing metabolic process cellular process protein metabolic process macromolecule metabolic process plasminogen activation	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR036120	Staphylokinase/Streptokinase superfamily	Homologous Superfamily
A, B, C, D	IPR008124	Streptokinase	Family
A, B, C, D	IPR004093	Staphylokinase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.