1BRL

THREE-DIMENSIONAL STRUCTURE OF BACTERIAL LUCIFERASE FROM VIBRIO HARVEYI AT 2.4 ANGSTROMS RESOLUTION

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1brla_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Bacterial luciferase-like	Bacterial luciferase (alkanal monooxygenase)	Bacterial luciferase alpha chain, LuxA	(Vibrio harveyi ) [TaxId: 669 ],	SCOPe (2.08)
C	d1brlc_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Bacterial luciferase-like	Bacterial luciferase (alkanal monooxygenase)	Bacterial luciferase alpha chain, LuxA	(Vibrio harveyi ) [TaxId: 669 ],	SCOPe (2.08)
B	d1brlb_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Bacterial luciferase-like	Bacterial luciferase (alkanal monooxygenase)	Bacterial luciferase beta chain, LuxB	(Vibrio harveyi ) [TaxId: 669 ],	SCOPe (2.08)
D	d1brld_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Bacterial luciferase-like	Bacterial luciferase (alkanal monooxygenase)	Bacterial luciferase beta chain, LuxB	(Vibrio harveyi ) [TaxId: 669 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Bacterial luciferase (alkanal monooxygenase)	8031441	4003312	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Bacterial luciferase-like	8043819	3000585	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	Bacterial luciferase-like	8043819	3000585	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Bacterial luciferase-like	8043817	3000585	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Bacterial luciferase-like	8043817	3000585	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00296	e1brlA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: PF00296	ECOD (1.6)
C	PF00296	e1brlC1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: PF00296	ECOD (1.6)
B	PF00296	e1brlB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: PF00296	ECOD (1.6)
D	PF00296	e1brlD1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: PF00296	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.30	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Luciferase-like domain	CATH (4.3.0)
C	3.20.20.30	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Luciferase-like domain	CATH (4.3.0)
B	3.20.20.30	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Luciferase-like domain	CATH (4.3.0)
D	3.20.20.30	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Luciferase-like domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF00296	Luciferase-like monooxygenase (Bac_luciferase)	Luciferase-like monooxygenase	-	Domain
B, D	PF00296	Luciferase-like monooxygenase (Bac_luciferase)	Luciferase-like monooxygenase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	BACTERIAL LUCIFERASE	oxidoreductase activity monooxygenase activity alkanal monooxygenase (FMN-linked) activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen catalytic activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	bioluminescence cellular metabolic process metabolic process cellular process	-
B, D	BACTERIAL LUCIFERASE	oxidoreductase activity monooxygenase activity alkanal monooxygenase (FMN-linked) activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen catalytic activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	bioluminescence cellular metabolic process metabolic process cellular process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR011251	Luciferase-like domain	Domain
A, C	IPR002103	Bacterial luciferase/NFP	Family
A, C	IPR033924	Alkanal monooxygenase	Family
A, C	IPR018235	Bacterial luciferase, conserved site	Conserved Site
A, C	IPR036661	Luciferase-like domain superfamily	Homologous Superfamily
B, D	IPR011251	Luciferase-like domain	Domain
B, D	IPR002103	Bacterial luciferase/NFP	Family
B, D	IPR033924	Alkanal monooxygenase	Family
B, D	IPR018235	Bacterial luciferase, conserved site	Conserved Site
B, D	IPR036661	Luciferase-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.