Annotations: 1BOL

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1bola_	Alpha and beta proteins (a+b)	Ribonuclease Rh-like	Ribonuclease Rh-like	Ribonuclease Rh-like	Ribonuclease Rh	(Rhizopus niveus ) [TaxId: 4844 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Ribonuclease Rh-like	8023839	4001977	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Ribonuclease Rh-like	8036219	3000632	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00445	e1bolA1	A: a+b two layers	X: Ribonuclease Rh-like (From Topology)	H: Ribonuclease Rh-like (From Topology)	T: Ribonuclease Rh-like	F: PF00445	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.90.730.10	Alpha Beta	Alpha-Beta Complex	Ribonuclease Rh	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00445	Ribonuclease T2 family (Ribonuclease_T2)	Ribonuclease T2 family	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	PROTEIN (RIBONUCLEASE RH)	endonuclease activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity phosphorus-oxygen lyase activity nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity lyase activity catalytic activity ribonuclease T2 activity RNA binding binding endonuclease activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity phosphorus-oxygen lyase activity nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity lyase activity catalytic activity ribonuclease T2 activity RNA binding binding organic cyclic compound binding nucleic acid binding	catabolic process RNA metabolic process primary metabolic process nucleic acid metabolic process macromolecule catabolic process organic cyclic compound catabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process nucleic acid catabolic process metabolic process macromolecule metabolic process organic substance catabolic process catabolic process RNA metabolic process primary metabolic process nucleic acid metabolic process macromolecule catabolic process organic cyclic compound catabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process nucleic acid catabolic process metabolic process macromolecule metabolic process organic substance catabolic process RNA catabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR018188	Ribonuclease T2, His active site 1	Active Site
A	IPR001568	Ribonuclease T2-like	Family
A	IPR033697	Ribonuclease T2, eukaryotic	Family
A	IPR036430	Ribonuclease T2-like superfamily	Homologous Superfamily
A	IPR033130	Ribonuclease T2, His active site 2	Active Site

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	ribonuclease T2 M-CSA #426	This represents a new class of ribonucleases having only very little sequence identity to existing classes. It is known to be base non-specific.	Defined by 6 residues: HIS:A-46TRP:A-49TYR:A-57GLU:A-105LYS:A-108HIS:A-109 \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 3.1.27.1 (PDB Primary Data) Search M-CSA Motif + EC 3.1.27.1

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