Annotations: 1AX3

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1ax3a_	All beta proteins	Barrel-sandwich hybrid	Duplicated hybrid motif	Glucose permease-like	Glucose permease IIa domain, IIa-glc	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PTS_EIIA_1	e1ax3A1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Duplicated hybrid motif	F: PTS_EIIA_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.70.10	Mainly Beta	Distorted Sandwich	Glucose Permease (Domain IIA)	Glucose Permease (Domain IIA)	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00358	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PTS_EIIA_1)	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	GLUCOSE PERMEASE IIA DOMAIN	kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups active transmembrane transporter activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity phosphotransferase activity, alcohol group as acceptor protein-phosphocysteine-sugar phosphotransferase activity glucose transmembrane transporter activity monosaccharide transmembrane transporter activity sugar transmembrane transporter activity kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups active transmembrane transporter activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity phosphotransferase activity, alcohol group as acceptor protein-phosphocysteine-sugar phosphotransferase activity glucose transmembrane transporter activity monosaccharide transmembrane transporter activity sugar transmembrane transporter activity D-glucose transmembrane transporter activity hexose transmembrane transporter activity D-glucosamine PTS permease activity	import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization transmembrane transport localization cellular process carbohydrate transmembrane transport phosphorylation cellular metabolic process import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization transmembrane transport localization cellular process carbohydrate transmembrane transport phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process phosphorus metabolic process	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR018113	Phosphotransferase system EIIB, cysteine phosphorylation site	Conserved Site
A	IPR013013	Phosphotransferase system, EIIC component, type 1	Domain
A	IPR001127	Phosphotransferase system, sugar-specific permease EIIA type 1	Domain
A	IPR011299	PTS system glucose-specific IIBC component	Domain
A	IPR011055	Duplicated hybrid motif	Homologous Superfamily
A	IPR036878	Glucose permease domain IIB	Homologous Superfamily
A	IPR001996	Phosphotransferase system, IIB component, type 1	Domain
A	IPR004719	Phosphotransferase system, maltose/glucose-specific subfamily IIC component	Domain
A	IPR003352	Phosphotransferase system, EIIC	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.