1AON

CRYSTAL STRUCTURE OF THE ASYMMETRIC CHAPERONIN COMPLEX GROEL/GROES/(ADP)7

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1aona1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
A	d1aona2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
A	d1aona3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1aonb1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1aonb2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1aonb3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
C	d1aonc1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
C	d1aonc2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
C	d1aonc3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
D	d1aond1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
D	d1aond2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
D	d1aond3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
E	d1aone1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
E	d1aone2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
E	d1aone3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
F	d1aonf1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
F	d1aonf2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
F	d1aonf3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
G	d1aong1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
G	d1aong2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
G	d1aong3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
H	d1aonh1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
H	d1aonh2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
H	d1aonh3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
I	d1aoni1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
I	d1aoni2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
I	d1aoni3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
J	d1aonj1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
J	d1aonj2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
J	d1aonj3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
K	d1aonk1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
K	d1aonk2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
K	d1aonk3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
L	d1aonl1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
L	d1aonl2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
L	d1aonl3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
M	d1aonm1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
M	d1aonm2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
M	d1aonm3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
N	d1aonn1	All alpha proteins	GroEL equatorial domain-like	GroEL equatorial domain-like	GroEL chaperone, ATPase domain	GroEL, E domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
N	d1aonn2	Alpha and beta proteins (a/b)	The 'swivelling' beta/beta/alpha domain	GroEL apical domain-like	GroEL-like chaperone, apical domain	GroEL, A domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
N	d1aonn3	Alpha and beta proteins (a+b)	GroEL-intermediate domain like	GroEL-intermediate domain like	GroEL-like chaperone, intermediate domain	GroEL, I domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
O	d1aono_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
P	d1aonp_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
Q	d1aonq_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
R	d1aonr_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
S	d1aons_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
T	d1aont_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
U	d1aonu_	All beta proteins	GroES-like	GroES-like	GroES	Chaperonin-10 (GroES)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL apical domain-like	8043929	3000963	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL equatorial domain-like	8032389	3001651	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	GroEL-intermediate domain like	8032390	3001087	SCOP2B (2022-06-29)
O	SCOP2 Family	GroES chaperonin-like	8002346	4000251	SCOP2 (2022-06-29)
O	SCOP2 Superfamily	GroES-like	8002348	3000002	SCOP2 (2022-06-29)
P	SCOP2B Superfamily	GroES-like	8002348	3000002	SCOP2B (2022-06-29)
Q	SCOP2B Superfamily	GroES-like	8002348	3000002	SCOP2B (2022-06-29)
R	SCOP2B Superfamily	GroES-like	8002348	3000002	SCOP2B (2022-06-29)
S	SCOP2B Superfamily	GroES-like	8002348	3000002	SCOP2B (2022-06-29)
T	SCOP2B Superfamily	GroES-like	8002348	3000002	SCOP2B (2022-06-29)
U	SCOP2B Superfamily	GroES-like	8002348	3000002	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Cpn60_TCP1_1st	e1aonA1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
A	Cpn60_TCP1_2nd_2	e1aonA3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
A	Cpn60_TCP1_3rd	e1aonA2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
B	Cpn60_TCP1_1st	e1aonB1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
B	Cpn60_TCP1_2nd_2	e1aonB3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
B	Cpn60_TCP1_3rd	e1aonB2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
C	Cpn60_TCP1_1st	e1aonC1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
C	Cpn60_TCP1_2nd_2	e1aonC3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
C	Cpn60_TCP1_3rd	e1aonC2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
D	Cpn60_TCP1_1st	e1aonD1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
D	Cpn60_TCP1_2nd_2	e1aonD3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
D	Cpn60_TCP1_3rd	e1aonD2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
E	Cpn60_TCP1_1st	e1aonE1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
E	Cpn60_TCP1_2nd_2	e1aonE3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
E	Cpn60_TCP1_3rd	e1aonE2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
F	Cpn60_TCP1_1st	e1aonF1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
F	Cpn60_TCP1_2nd_2	e1aonF3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
F	Cpn60_TCP1_3rd	e1aonF2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
G	Cpn60_TCP1_1st	e1aonG1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
G	Cpn60_TCP1_2nd_2	e1aonG3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
G	Cpn60_TCP1_3rd	e1aonG2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
H	Cpn60_TCP1_1st	e1aonH1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
H	Cpn60_TCP1_2nd_2	e1aonH3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
H	Cpn60_TCP1_3rd	e1aonH2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
I	Cpn60_TCP1_1st	e1aonI1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
I	Cpn60_TCP1_2nd_2	e1aonI3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
I	Cpn60_TCP1_3rd	e1aonI2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
J	Cpn60_TCP1_1st	e1aonJ1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
J	Cpn60_TCP1_2nd_2	e1aonJ3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
J	Cpn60_TCP1_3rd	e1aonJ2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
K	Cpn60_TCP1_1st	e1aonK1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
K	Cpn60_TCP1_2nd_2	e1aonK3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
K	Cpn60_TCP1_3rd	e1aonK2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
L	Cpn60_TCP1_1st	e1aonL1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
L	Cpn60_TCP1_2nd_2	e1aonL3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
L	Cpn60_TCP1_3rd	e1aonL2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
M	Cpn60_TCP1_1st	e1aonM1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
M	Cpn60_TCP1_2nd_2	e1aonM3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
M	Cpn60_TCP1_3rd	e1aonM2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
N	Cpn60_TCP1_1st	e1aonN1	A: alpha bundles	X: GroEL equatorial domain-like (From Topology)	H: GroEL equatorial domain-like (From Topology)	T: GroEL equatorial domain-like	F: Cpn60_TCP1_1st	ECOD (1.6)
N	Cpn60_TCP1_2nd_2	e1aonN3	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: Cpn60_TCP1_2nd_2	ECOD (1.6)
N	Cpn60_TCP1_3rd	e1aonN2	A: mixed a+b and a/b	X: Zincin-like	H: GroEL-intermediate domain like (From Topology)	T: GroEL-intermediate domain like	F: Cpn60_TCP1_3rd	ECOD (1.6)
O	Cpn10	e1aonO1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
P	Cpn10	e1aonP1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
Q	Cpn10	e1aonQ1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
R	Cpn10	e1aonR1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
S	Cpn10	e1aonS1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
T	Cpn10	e1aonT1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)
U	Cpn10	e1aonU1	A: beta barrels	X: GroES-like	H: GroES-related	T: GroES	F: Cpn10	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
A	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
A	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
B	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
B	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
B	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
C	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
C	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
C	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
D	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
D	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
D	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
E	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
E	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
E	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
F	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
F	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
F	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
G	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
G	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
G	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
H	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
H	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
H	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
I	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
I	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
I	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
J	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
J	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
J	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
K	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
K	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
K	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
L	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
L	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
L	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
M	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
M	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
M	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
N	1.10.560.10	Mainly Alpha	Orthogonal Bundle	GROEL	domain 1	CATH (4.3.0)
N	3.30.260.10	Alpha Beta	2-Layer Sandwich	GROEL	domain 2	CATH (4.3.0)
N	3.50.7.10	Alpha Beta	3-Layer(bba) Sandwich	GroEL	GroEL	CATH (4.3.0)
O	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
P	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
Q	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
R	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
S	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
T	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)
U	2.30.33.40	Mainly Beta	Roll	10 Kd Chaperonin, Protein Cpn10	Chain O	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	PF00118	TCP-1/cpn60 chaperonin family (Cpn60_TCP1)	TCP-1/cpn60 chaperonin family	-	Family
O, P, Q, R, S O, P, Q, R, S, T, U	PF00166	Chaperonin 10 Kd subunit (Cpn10)	Chaperonin 10 Kd subunit	This family contains GroES and Gp31-like chaperonins. Gp31 is a functional co-chaperonin that is required for the folding and assembly of Gp23, a major capsid protein, during phage morphogenesis [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	GROEL	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding unfolded protein binding protein binding isomerase activity catalytic activity pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides ATP-dependent activity ATP-dependent protein folding chaperone protein folding chaperone identical protein binding	protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein refolding organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process chaperone cofactor-dependent protein refolding chaperone-mediated protein folding 'de novo' protein folding 'de novo' post-translational protein folding virion assembly viral process viral life cycle response to stimulus response to radiation response to abiotic stimulus response to stress response to heat response to temperature stimulus	membrane cellular anatomical entity protein-containing complex chaperonin ATPase complex intracellular anatomical structure protein folding chaperone complex GroEL-GroES complex cytoplasm cytosol intracellular protein-containing complex
O, P, Q, R, S O, P, Q, R, S, T, U	GROEL/GROES COMPLEX	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding unfolded protein binding protein binding protein folding chaperone cation binding metal ion binding protein-folding chaperone binding identical protein binding	organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process organonitrogen compound metabolic process cellular biosynthetic process cellular metabolic process primary metabolic process gene expression macromolecule biosynthetic process protein maturation organic substance metabolic process protein folding biosynthetic process organic substance biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process chaperone cofactor-dependent protein refolding chaperone-mediated protein folding 'de novo' protein folding 'de novo' post-translational protein folding virion assembly viral process viral life cycle response to stimulus response to stress response to heat response to abiotic stimulus response to temperature stimulus	protein-containing complex chaperonin ATPase complex intracellular anatomical structure protein folding chaperone complex GroEL-GroES complex cytoplasm cellular anatomical entity cytosol intracellular protein-containing complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027413	GroEL-like equatorial domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027410	TCP-1-like chaperonin intermediate domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR001844	Chaperonin Cpn60/GroEL	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR018370	Chaperonin Cpn60, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR027409	GroEL-like apical domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N	IPR002423	Chaperonin Cpn60/GroEL/TCP-1 family	Family
O, P, Q, R, S O, P, Q, R, S, T, U	IPR018369	Chaperonin GroES, conserved site	Conserved Site
O, P, Q, R, S O, P, Q, R, S, T, U	IPR011032	GroES-like superfamily	Homologous Superfamily
O, P, Q, R, S O, P, Q, R, S, T, U	IPR037124	GroES chaperonin superfamily	Homologous Superfamily
O, P, Q, R, S O, P, Q, R, S, T, U	IPR020818	GroES chaperonin family	Family