5ZHX
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
E [auth e] | SCOP2B Superfamily | Ras-like P-loop GTPases | 8057414 | 3002022 | SCOP2B (2022-06-29) |
F [auth f] | SCOP2B Superfamily | Ras-like P-loop GTPases | 8057414 | 3002022 | SCOP2B (2022-06-29) |
G [auth g] | SCOP2B Superfamily | Ras-like P-loop GTPases | 8057414 | 3002022 | SCOP2B (2022-06-29) |
H [auth h] | SCOP2B Superfamily | Ras-like P-loop GTPases | 8057414 | 3002022 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00514 | e5zhxA1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: ARM repeat (From Topology) | T: ARM repeat | F: PF00514 | ECOD (1.6) |
B | PF00514 | e5zhxB1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: ARM repeat (From Topology) | T: ARM repeat | F: PF00514 | ECOD (1.6) |
C | PF00514 | e5zhxC1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: ARM repeat (From Topology) | T: ARM repeat | F: PF00514 | ECOD (1.6) |
D | PF00514 | e5zhxD1 | A: alpha superhelices | X: Repetitive alpha hairpins | H: ARM repeat (From Topology) | T: ARM repeat | F: PF00514 | ECOD (1.6) |
E [auth e] | PF00071 | e5zhxe1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00071 | ECOD (1.6) |
F [auth f] | PF00071 | e5zhxf1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00071 | ECOD (1.6) |
G [auth g] | PF00071 | e5zhxg1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00071 | ECOD (1.6) |
H [auth h] | PF00071 | e5zhxh1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00071 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
E [auth e] | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
F [auth f] | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
G [auth g] | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
H [auth h] | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00514 | Armadillo/beta-catenin-like repeat (Arm) | Armadillo/beta-catenin-like repeat | - | Repeat | |
E [auth e], F [auth f], G [auth g], H [auth h] | PF00071 | Ras family (Ras) | Ras family | Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head. See Pfam:PF00009 Pfam:PF00025, Pfam:PF00063. As regards Rab GTPases, these are important regulators of vesicle formation, motil ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR040144 | Rap1 GTPase-GDP dissociation stimulator 1 | Family | |
IPR016024 | Armadillo-type fold | Homologous Superfamily | |
IPR000225 | Armadillo | Repeat | |
IPR011989 | Armadillo-like helical | Homologous Superfamily | |
E [auth e], F [auth f], G [auth g], H [auth h] | IPR001806 | Small GTPase | Family |
E [auth e], F [auth f], G [auth g], H [auth h] | IPR003578 | Small GTPase Rho | Family |
E [auth e], F [auth f], G [auth g], H [auth h] | IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily |
E [auth e], F [auth f], G [auth g], H [auth h] | IPR005225 | Small GTP-binding protein domain | Domain |