2L7Q

Solution NMR structure of conjugate transposon protein BVU_1572(27-141) from Bacteroides Vulgatus, Northeast Structural Genomics Consortium Target BvR155


Experimental Data Snapshot

  • Method: SOLUTION NMR
  • Conformers Calculated: 150 
  • Conformers Submitted: 20 
  • Selection Criteria: structures with the lowest energy 

wwPDB Validation   3D Report Full Report


This is version 1.7 of the entry. See complete history


Literature

Solution NMR structure of BT_0084, a conjugative transposon lipoprotein from Bacteroides thetaiotamicron.

Ramelot, T.A.Yang, Y.Xiao, R.Acton, T.B.Everett, J.K.Montelione, G.T.Kennedy, M.A.

(2012) Proteins 80: 667-670

  • DOI: https://doi.org/10.1002/prot.23235
  • Primary Citation of Related Structures:  
    2L3B, 2L7Q

  • PubMed Abstract: 

    Here we describe the solution NMR structure of the 120 amino acid fragment of BT_0084, without the N-terminal lipoprotein targeting sequence, encoded in a conjugative transposon (CTn) in the genome of Bacteroides thetaiotamicron. BT_0084 belongs to a conserved family of TraQ lipoproteins that are encoded at the end of the tra operon, which contains genes essential for transfer of CTns. The structure belongs to the immunoglobulin superfamily and shares structural similarity, albeit low sequence identity (< 15%), to other proteins involved in pili production for bacterial cell attachment. Although its role in repression of CTn transfer remains to be determined, the structure of BT_0084 reported here represents the first from the Bacteroides TraQ family and should facilitate further understanding of the tra operon-regulated transfer of CTns.


  • Organizational Affiliation

    Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio 45056 and the Northeast Structural Genomics Consortium. ramelota@muohio.edu.


Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Conserved protein found in conjugate transposon124Phocaeicola vulgatus ATCC 8482Mutation(s): 0 
Gene Names: BVU_1572
UniProt
Find proteins for A6L0P5 (Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154))
Explore A6L0P5 
Go to UniProtKB:  A6L0P5
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupA6L0P5
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: SOLUTION NMR
  • Conformers Calculated: 150 
  • Conformers Submitted: 20 
  • Selection Criteria: structures with the lowest energy 

Structure Validation

View Full Validation Report



Entry History 

Revision History  (Full details and data files)

  • Version 1.0: 2010-12-29
    Type: Initial release
  • Version 1.1: 2011-07-13
    Changes: Version format compliance
  • Version 1.2: 2011-12-14
    Changes: Database references
  • Version 1.3: 2012-02-22
    Changes: Structure summary
  • Version 1.4: 2013-01-30
    Changes: Database references
  • Version 1.5: 2013-03-06
    Changes: Database references
  • Version 1.6: 2023-06-14
    Changes: Data collection, Database references, Other
  • Version 1.7: 2024-05-15
    Changes: Data collection, Database references