Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex.
Ye, X., Kumar, R.A., Patel, D.J.(1995) Chem Biol 2: 827-840
- PubMed: 8807816 
- DOI: https://doi.org/10.1016/1074-5521(95)90089-6
- Primary Citation of Related Structures:  
1BIV - PubMed Abstract: 
In lentiviruses such as human immunodeficiency virus (HIV) and bovine immunodeficiency virus (BIV), the Tat (trans-activating) protein enhances transcription of the viral RNA by complexing to the 5'-end of the transcribed mRNA, at a region known as TAR (the trans-activation response element). Identification of the determinants that account for specific molecular recognition requires a high resolution structure of the Tat peptide-TAR RNA complex.
Organizational Affiliation: 
Cellular Biochemistry & Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.