POP-OUT | CLOSE
MyPDB Login - Username: Password:

About: MyPDB stores and automatically runs your favorite queries. Email alerts are sent when matching structures are found.

    MyPDB Login
MyPDB: Login | Register
A Member of the wwPDB

An Information Portal to Biological Macromolecular Structures

As of Tuesday Mar 09, 2010 at 4 PM PST there are 63956 Structures RSS Feed for the Latest Released Structures Help | Latest Released  |  PDB Statistics Help | PDB Statistics
RCSB PDB Protein Data Bank | Home

Print Options: BW Safe Color Safe Print




URL:
 


Molecule of the Month March 2010
P-glycoprotein

Molecule of the Month

The RCSB PDB Molecule of the Month by David S. Goodsell (The Scripps Research Institute and the RCSB PDB) presents short accounts on selected molecules from the Protein Data Bank. Each installment includes an introduction to the structure and function of the molecule, a discussion of the relevance of the molecule to human health and welfare, and suggestions for how visitors might view these structures and access further details.

This feature provides an easy introduction to the RCSB PDB for all types of users, but especially for teachers and students. It is used in many classrooms to introduce structures to students, and is an integral part of the protein modeling event at the Science Olympiad. It is not intended to be a comprehensive index to entries in the PDB archive, nor necessarily represent the historical record. The structures used to illustrate each installment are chosen at the discretion of the authors. Goodsell described the creation of these articles and images in an interview with the RCSB PDB Newsletter.

The structure features below are also available in an alphabetical listing. Citation and usage information is available. High resolution TIFF images are also available.

Other institutions publish similar features, including the Protein of the Month at the European Bioinformatics Institute and Protein Spotlight at the Swiss Institute of Bioinformatics.

Archives

70S Ribosomes
2010 Mar P-glycoprotein
Feb Enhanceosome
Jan 70S Ribosomes

Tobacco Mosaic Virus
2009 Dec Antifreeze Proteins
Nov Designed DNA Crystal
Oct Sodium-Potassium Pump
Sep Xanthine Oxidoreductase
Aug Sulfotransferases
Jul beta-Secretase
Jun Vaults
May Influenza Neuraminidase (PDF 436 KB)
Apr Oct and Sox Transcription Factors
Mar Hydrogenase
Feb Auxin and TIR1 Ubiquitin Ligase
Jan Tobacco Mosaic Virus (PDF 556 KB)

Circadian Clock Proteins
2008 Dec Hsp90 (PDF 352 KB)
Nov Mechanosensitive Channels (PDF 440 KB)
Oct Poly(A) Polymerase (PDF 396 KB)
Sep Ribonuclease A (PDF 284 KB)
Aug Selenocysteine Synthase (PDF 280 KB)
Jul Dengue Virus (PDF 332 KB)
Jun Lactate Dehydrogenase (PDF 396 KB)
May Prions (PDF 356 KB)
Apr Adrenergic Receptors (PDF 236 KB)
Mar Cadherin (PDF 688 KB)
Feb Small Interfering RNA (siRNA) (PDF 1.2 MB)
Jan Circadian Clock Proteins (PDF 1 MB)

Importins
2007 Dec Oxidosqualene Cyclase (PDF 1.6 MB)
Nov Multidrug Resistance Transporters (PDF 1.2 MB)
Oct Superoxide Dismutase (PDF 836 KB)
Sep Citrate Synthase (PDF 936 KB)
Aug Anabolic Steroids (PDF 1 MB)
Jul Thymine Dimers (PDF 1.1 MB)
Jun Fatty Acid Synthase (PDF 1.4 MB)
May Aconitase and Iron Regulatory Protein 1 (PDF 1.19 MB)
Apr Clathrin (PDF 1.16 MB)
Mar Zinc Fingers (PDF 1.3 MB)
Feb Exosomes (PDF 1.1 MB)
Jan Importins (PDF 1 MB)

Topoisomerases
2006 Dec Transposase (PDF 865 KB)
Nov Fibrin (PDF 712 KB)
Oct Cytochrome p450 (PDF 735 KB)
Sep Elongation Factors (PDF 1.4 MB)
Aug AAA+ Proteases (PDF 1.3 MB)
Jul Amyloid-beta Precursor Protein (PDF 866 KB)
Jun Luciferase (PDF 904 KB)
May Glucose Oxidase (PDF 300 KB)
Apr Hemagglutinin (PDF 310 KB)
Mar Tissue Factor (PDF 308 KB)
Feb Alpha-amylase (PDF 412 KB)
Jan Topoisomerases (PDF 378 KB)

Phenylalanine Hydroxylase
2005 Dec ATP Synthase (PDF 334 KB)
Nov Acetylcholine Receptor (PDF 487 KB)
Oct Designer Proteins (PDF 363 KB)
Sep Cholera Toxin (PDF 373 KB)
Aug Neurotrophins (PDF 270 KB)
Jul TATA-Binding Protein (PDF 405 KB)
Jun Carotenoid Oxygenase (PDF 312 KB)
May Self-splicing RNA (PDF 278 KB)
Apr Kinesin (PDF 274 KB)
Mar T-Cell Receptor (PDF 351 KB)
Feb Major Histocompatibility Complex (PDF 462 KB)
Jan Phenylalanine Hydroxylase (PDF 477 KB)

Carbonic Anhydrase
2004 Dec Ubiquitin (PDF 315 KB)
Nov Photosystem II (PDF 1.2 MB)
Oct G Proteins (PDF 293 KB)
Sep Catalase (PDF 430 KB)
Aug Caspases (PDF 340 KB)
Jul DNA Ligase (PDF 330 KB)
Jun Acetylcholinesterase (PDF 321 KB)
May Serpins (PDF 346 KB)
Apr Growth Hormone (PDF 210 KB)
Mar Calcium Pump (PDF 315 KB)
Feb Glycolytic Enzymes (PDF 970 KB)
Jan Carbonic Anhydrase (PDF 260 KB)

Serum Albumin
2003 Dec Catabolite Activator Protein (PDF 3.6 MB)
Nov Simian Virus 40 (PDF 388 KB)
Oct Trypsin (PDF 405 KB)
Sep Estrogen Receptor (PDF 345 KB)
Aug Calmodulin (PDF 353 KB)
Jul Src Tyrosine Kinase (PDF 312 KB)
Jun Green Fluorescent Protein (GFP) (PDF 262 KB)
May Hemoglobin (PDF 2.0 MB)
Apr RNA Polymerase (PDF 278 KB)
Mar lac Repressor (PDF 511 KB)
Feb Potassium Channels (PDF 561 KB)
Jan Serum Albumin (PDF 257 KB)

Thrombin
2002 Dec Cytochrome c (PDF 339 KB)
Nov Ferritin and Transferrin (PDF 394 KB)
Oct Dihydrofolate Reductase (PDF 235 KB)
Sep Reverse Transcriptase (PDF 305 KB)
Aug Chaperones (PDF 456 KB)
Jul p53 Tumor Suppressor (PDF 348 KB)
Jun Glutamine Synthetase (PDF 1.1 MB)
May Penicillin-binding Proteins (PDF 243 KB)
Apr Anthrax Toxin (PDF 488 KB)
Mar Bacteriorhodopsin (PDF 358 KB)
Feb Nitrogenase (PDF 430 KB)
Jan Thrombin (PDF 344 KB)

Alcohol Dehydrogenase
2001 Dec Glycogen Phosphorylase (PDF 365 KB)
Nov DNA (PDF 324 KB)
Oct Photosystem I (PDF 580 KB)
Sep Antibodies (PDF 363 KB)
Aug Poliovirus and Rhinovirus (PDF 440 KB)
Jul Actin (PDF 278 KB)
Jun Myosin (PDF 331 KB)
May Cyclooxygenase (PDF 237 KB)
Apr Aminoacyl-tRNA Synthetases (PDF 445 KB)
Mar Transfer RNA (PDF 230 KB)
Feb Insulin (PDF 150 KB)
Jan Alcohol Dehydrogenase (PDF 266 KB)

Myoglobin
2000 Dec Pepsin (PDF 394 KB)
Nov Rubisco (PDF 265 KB)
Oct Ribosome (PDF 347 KB)
Sep Lysozyme (PDF 211 KB)
Aug Restriction Enzymes (PDF 195 KB)
Jul Nucleosome (PDF 256 KB)
Jun HIV-1 Protease (PDF 215 KB)
May Cytochrome c Oxidase (PDF 244 KB)
Apr Collagen (PDF 346 KB)
Mar DNA Polymerase (PDF 261 KB)
Feb Bacteriophage phiX174 (PDF 200 KB)
Jan Myoglobin (PDF 138 KB)