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FLAVIN-ADENINE DINUCLEOTIDE
 
FAD is found in 1524 entries
FAD
  •   Chemical Component Summary   Hide
    Name FLAVIN-ADENINE DINUCLEOTIDE
    Identifiers [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name)
    [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-benzo[g]pteridin-10-yl)-2,3,4-trihydroxy-pentoxy]-hydroxy-phosphoryl] hydrogen phosphate
    Formula C27 H33 N9 O15 P2
    Molecular Weight 785.55 g/mol
    Type non-polymer
    Isomeric SMILES
    InChI
    InChI key VWWQXMAJTJZDQX-UYBVJOGSSA-N
     
  •   Drug Info: DrugBank Hide
    DrugBank ID DB03147   (Stereoisomeric match)
    Name Flavin adenine dinucleotide
    Groups approved
    Description A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
    Synonyms
    • Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine
    • Adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate]
    • FAD
    • Flavin adenine dinucleotide
    • FLAVIN-adenine dinucleotide
    • Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine
    • Riboflavin 5'-adenosine diphosphate
    [more]
    Salts Flavin adenine dinucleotide sodium
    Brand names
    • Adeflavin
    • Flaziren
    Affected organism Humans and other mammals
    Indication Used to treat eye diseases caused by vitamin B2 deficiency, such as keratitis and blepharitis.
    Route of administration Ophthalmic
    CAS number 146-14-5
    Targets
    Name Sequence search Pharmacological action Actions
    Nitric oxide synthase, brain   Search  unknown
    D-lactate dehydrogenase   Search  unknown
    NADH-cytochrome b5 reductase 3   Search  unknown
    Ribosyldihydronicotinamide dehydrogenase [quinone]   Search  unknown
    Glutathione reductase   Search  unknown
    [more]
     
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