7PZT

Structure of the bacterial toxin, TecA, an asparagine deamidase from Alcaligenes faecalis.


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.84 Å
  • R-Value Free: 0.233 
  • R-Value Work: 0.190 

wwPDB Validation   3D Report Full Report


This is version 1.0 of the entry. See complete history


Literature

The structure of A. faecalis TecA provides insights into its role as an asparagine deamidase toxin which targets RhoA

Dix, S.R.Aziz, A.A.Baker, B.J.Evans, C.A.Dickman, M.J.Farthing, R.J.King, Z.L.S.Nathan, S.Partridge, L.J.Raih, F.M.Sedelnikova, S.E.Thomas, M.S.Rice, D.W.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Urea amidohydrolase
A, B
160Alcaligenes faecalisMutation(s): 0 
Gene Names: D0C27_02010
UniProt
Find proteins for A0A4P8JK46 (Alcaligenes faecalis)
Explore A0A4P8JK46 
Go to UniProtKB:  A0A4P8JK46
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupA0A4P8JK46
Sequence Annotations
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  • Reference Sequence
Small Molecules
Ligands 1 Unique
IDChains Name / Formula / InChI Key2D Diagram3D Interactions
MES
Query on MES

Download Ideal Coordinates CCD File 
C [auth B]2-(N-MORPHOLINO)-ETHANESULFONIC ACID
C6 H13 N O4 S
SXGZJKUKBWWHRA-UHFFFAOYSA-N
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 1.84 Å
  • R-Value Free: 0.233 
  • R-Value Work: 0.190 
  • Space Group: P 21 21 21
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 47.051α = 90
b = 71.407β = 90
c = 95.923γ = 90
Software Package:
Software NamePurpose
REFMACrefinement
DIALSdata reduction
DIALSdata scaling
CRANK2phasing

Structure Validation

View Full Validation Report



Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
Royal SocietyUnited KingdomIC170306
Biotechnology and Biological Sciences Research Council (BBSRC)United KingdomBB/M012166/1

Revision History  (Full details and data files)

  • Version 1.0: 2022-11-02
    Type: Initial release