Download MendeleyCrystal structure of the WD-repeat domain of human KIF21A
Zeng, H., Dong, A., Loppnau, P., Hutchinson, A., Seitova, A., Edwards, A.M., Arrowsmith, C.H., Halabelian, L.To be published.
7KLJ
Crystal structure of the WD-repeat domain of human KIF21A
- PDB DOI: https://doi.org/10.2210/pdb7KLJ/pdb
- Classification: MOTOR PROTEIN
- Organism(s): Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): No
- Deposited: 2020-10-30 Released: 2020-12-16
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.52 Å
- R-Value Free: 0.185
- R-Value Work: 0.170
- R-Value Observed: 0.171
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Isoform 2 of Kinesin-like protein KIF21A | 335 | Homo sapiens | Mutation(s): 0 Gene Names: KIF21A, KIAA1708, KIF2 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q7Z4S6 (Homo sapiens) Explore Q7Z4S6 Go to UniProtKB: Q7Z4S6 | |||||
PHAROS: Q7Z4S6 GTEx: ENSG00000139116 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q7Z4S6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EDO Query on EDO | C [auth A], H [auth B] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| UNX Query on UNX | D [auth A], E [auth A], F [auth A], G [auth A], I [auth B] | UNKNOWN ATOM OR ION X |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.52 Å
- R-Value Free: 0.185
- R-Value Work: 0.170
- R-Value Observed: 0.171
- Space Group: P 1 21 1
- Diffraction Data: https://doi.org/10.18430/m37klj
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 55.275 | α = 90 |
| b = 67.067 | β = 94.43 |
| c = 79.88 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-3000 | data scaling |
| PDB_EXTRACT | data extraction |
| BALBES | phasing |
Entry History
Deposition Data
- Released Date: 2020-12-16 Deposition Author(s): Zeng, H., Dong, A., Loppnau, P., Hutchinson, A., Seitova, A., Edwards, A.M., Arrowsmith, C.H., Halabelian, L., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2020-12-16
Type: Initial release - Version 1.1: 2024-03-06
Changes: Data collection, Database references
