7CLV

Solution structure of mitochondrial Tim23 channel in complex with a signaling peptide

PDB DOI: https://doi.org/10.2210/pdb7CLV/pdb

Classification: PROTEIN TRANSPORT
Organism(s): Saccharomyces cerevisiae
Expression System: Escherichia coli K-12
Mutation(s): No
Membrane Protein: Yes OPMPDBTM

Deposited: 2020-07-22 Released: 2020-12-30
Deposition Author(s): Zhou, S., Ruan, M.S., Li, Y.Y., Yang, J., Richter, C., Schwalbe, H., Shen, B., Wang, J.F.
Funding Organization(s): Chinese Academy of Sciences

Experimental Data Snapshot

Method: SOLUTION NMR
Conformers Calculated: 100
Conformers Submitted: 15
Selection Criteria: structures with the lowest energy

wwPDB Validation 3D Report Full Report

This is version 1.2 of the entry. See complete history.

Literature

Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide.

Zhou, S., Ruan, M., Li, Y., Yang, J., Bai, S., Richter, C., Schwalbe, H., Xie, C., Shen, B., Wang, J.

(2021) Cell Res 31: 821-824

PubMed: 33318647 Search on PubMedSearch on PubMed Central
DOI: https://doi.org/10.1038/s41422-020-00452-y
Primary Citation of Related Structures:
7CLV

Organizational Affiliation

High Magnetic Field Laboratory, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, 230031, China. shu.zhou@hmfl.ac.cn.

Macromolecule Content

Total Structure Weight: 49.53 kDa
Atom Count: 3,471
Modelled Residue Count: 469
Deposited Residue Count: 469
Unique protein chains: 2

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
TIM23 isoform 1	A, B	222	Saccharomyces cerevisiae	Mutation(s): 0 Gene Names: TIM23, GI526_G0005095 Membrane Entity: Yes
UniProt
Find proteins for P32897 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c)) Explore P32897 Go to UniProtKB: P32897
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P32897
Sequence Annotations Expand
Reference Sequence

Find similar proteins by: Sequence | 3D Structure

Entity ID: 2
Molecule	Chains	Sequence Length	Organism	Details	Image
COX4 isoform 1	C	25	Saccharomyces cerevisiae	Mutation(s): 0 Gene Names: COX4, GI526_G0002212 Membrane Entity: Yes
UniProt
Find proteins for P04037 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c)) Explore P04037 Go to UniProtKB: P04037
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P04037
Sequence Annotations Expand
Reference Sequence