Download MendeleyNon-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3
Liu, Y.P., Lan, W.X., Wang, C.X., Cao, C.Y.To be published.
7D3V
Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A
- PDB DOI: https://doi.org/10.2210/pdb7D3V/pdb
- NAKB: 7D3V
- Classification: DNA BINDING PROTEIN/DNA
- Organism(s): Homo sapiens, synthetic construct
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2020-09-21 Released: 2021-10-06
Experimental Data Snapshot
- Method: SOLUTION NMR
- Conformers Calculated: 100
- Conformers Submitted: 20
- Selection Criteria: structures with the lowest energy
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| DNA dC->dU-editing enzyme APOBEC-3A | 199 | Homo sapiens | Mutation(s): 4 Gene Names: APOBEC3A EC: 3.5.4.38 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P31941 (Homo sapiens) Explore P31941 Go to UniProtKB: P31941 | |||||
PHAROS: P31941 GTEx: ENSG00000128383 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P31941 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar nucleic acids by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | Organism | Image | |
| DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3') | 10 | synthetic construct |  | ||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZN (Subject of Investigation/LOI) Query on ZN | E [auth A], F [auth B] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: SOLUTION NMR
- Conformers Calculated: 100
- Conformers Submitted: 20
- Selection Criteria: structures with the lowest energy
Entry History
Revision History (Full details and data files)
- Version 1.0: 2021-10-06
Type: Initial release - Version 1.1: 2023-06-14
Changes: Other
