Download MendeleyStructure of Choline kinase from Cryptococcus neoformans var. grubii serotype A
Abendroth, J., Delker, S.L., Lorimer, D.D., Horanyi, P.S., Edwards, T.E.To be published.
6WHP
Structure of Choline kinase from Cryptococcus neoformans var. grubii serotype A
- PDB DOI: https://doi.org/10.2210/pdb6WHP/pdb
- Classification: TRANSFERASE
- Organism(s): Cryptococcus neoformans var. grubii H99
- Expression System: Escherichia coli 'BL21-Gold(DE3)pLysS AG
- Mutation(s): No
- Deposited: 2020-04-08 Released: 2020-04-22
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.25 Å
- R-Value Free: 0.226
- R-Value Work: 0.181
- R-Value Observed: 0.185
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Choline kinase | 440 | Cryptococcus neoformans var. grubii H99 | Mutation(s): 0 Gene Names: CNAG_04408 |  | |
UniProt | |||||
Find proteins for J9VWY8 (Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)) Explore J9VWY8 Go to UniProtKB: J9VWY8 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | J9VWY8 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EDO Query on EDO | B [auth A], C [auth A], D [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| CL Query on CL | E [auth A], F [auth A], G [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.25 Å
- R-Value Free: 0.226
- R-Value Work: 0.181
- R-Value Observed: 0.185
- Space Group: H 3 2
- Diffraction Data: https://doi.org/10.18430/m36whp
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 129.5 | α = 90 |
| b = 129.5 | β = 90 |
| c = 160.01 | γ = 120 |
| Software Name | Purpose |
|---|---|
| XDS | data reduction |
| XSCALE | data scaling |
| PHENIX | refinement |
| PDB_EXTRACT | data extraction |
| MR-Rosetta | phasing |
| Coot | model building |
Entry History
Deposition Data
- Released Date: 2020-04-22 Deposition Author(s): Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Revision History (Full details and data files)
- Version 1.0: 2020-04-22
Type: Initial release - Version 1.1: 2024-03-06
Changes: Data collection, Database references - Version 1.2: 2024-04-03
Changes: Refinement description
