Download MendeleyStructure of DynF from the Dynemicin Biosynthesis Pathway of Micromonospora chersina
Kosgei, A.J., Miller, M.D., Xu, W., Van Lanen, S.G., Thorson, J.S., Phillips Jr., G.N.To be published.
6VQP
Structure of CalU17 from the Calicheamicin Biosynthesis Pathway of Micromonospora echinospora
- PDB DOI: https://doi.org/10.2210/pdb6VQP/pdb
- Classification: UNKNOWN FUNCTION
- Organism(s): Micromonospora echinospora
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2020-02-05 Released: 2021-02-17
- Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS), National Institutes of Health/National Cancer Institute (NIH/NCI), National Science Foundation (NSF, United States)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.226
- R-Value Work: 0.155
- R-Value Observed: 0.159
wwPDB Validation 3D Report Full Report
Currently 6VQP does not have a validation slider image.
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| CalU17 | 335 | Micromonospora echinospora | Mutation(s): 0 Gene Names: calU17 |  | |
UniProt | |||||
Find proteins for Q8KND1 (Micromonospora echinospora) Explore Q8KND1 Go to UniProtKB: Q8KND1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8KND1 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| CalU17 His-Tagged protein | B [auth Q] | 19 | Micromonospora echinospora | Mutation(s): 0 Gene Names: calU17 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GOL Query on GOL | E [auth A], F [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| MG Query on MG | C [auth A], D [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.226
- R-Value Work: 0.155
- R-Value Observed: 0.159
- Space Group: P 43 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 53.951 | α = 90 |
| b = 53.951 | β = 90 |
| c = 218.923 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
| PHASER | phasing |
| PDB_EXTRACT | data extraction |
Structure Validation
Currently 6VQP does not have a validation slider image.
Entry History & Funding Information
Deposition Data
- Released Date: 2021-02-17 Deposition Author(s): Kosgei, A.J., Miller, M.D., Xu, W., Van Lanen, S.G., Thorson, J.S., Phillips Jr., G.N.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | R01-GM115261 |
| National Institutes of Health/National Cancer Institute (NIH/NCI) | United States | R01-CA217255 |
| National Science Foundation (NSF, United States) | United States | STC-1231306 |
Revision History (Full details and data files)
- Version 1.0: 2021-02-17
Type: Initial release - Version 1.1: 2023-10-11
Changes: Data collection, Database references, Refinement description
