Download MendeleyCrystal Structure of Melanoma-associated antigen B1 (MAGEB1) in complex with nanobody
Ye, M., Newman, J., Pike, A.C.W., Burgess-Brown, N., Cooper, C.D.O., Bountra, C., Arrowsmith, C., Edwards, A., Gileadi, O., von Delft, F.To be published.
6R7T
Crystal Structure of human Melanoma-associated antigen B1 (MAGEB1) in complex with nanobody
- PDB DOI: https://doi.org/10.2210/pdb6R7T/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Lama glama, Homo sapiens
- Expression System: Escherichia coli 'BL21-Gold(DE3)pLysS AG
- Mutation(s): No
- Deposited: 2019-03-29 Released: 2019-05-01
- Funding Organization(s): Wellcome Trust
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.68 Å
- R-Value Free: 0.288
- R-Value Work: 0.258
- R-Value Observed: 0.259
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| anti MAGEB1 nanobody | 123 | Lama glama | Mutation(s): 0 |  | |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Melanoma-associated antigen B1 | 251 | Homo sapiens | Mutation(s): 0 Gene Names: MAGEB1, MAGEL1, MAGEXP |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P43366 (Homo sapiens) Explore P43366 Go to UniProtKB: P43366 | |||||
PHAROS: P43366 GTEx: ENSG00000214107 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P43366 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.68 Å
- R-Value Free: 0.288
- R-Value Work: 0.258
- R-Value Observed: 0.259
- Space Group: P 61 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 61.976 | α = 90 |
| b = 61.976 | β = 90 |
| c = 361.001 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| DIALS | data reduction |
| Aimless | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2019-05-01 Deposition Author(s): Ye, M., Newman, J., Pike, A.C.W., Burgess-Brown, N., Cooper, C.D.O., Bountra, C., Arrowsmith, C., Edwards, A., Gileadi, O., von Delft, F.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Wellcome Trust | United Kingdom | -- |
Revision History (Full details and data files)
- Version 1.0: 2019-05-01
Type: Initial release - Version 1.1: 2019-05-29
Changes: Data collection, Database references, Refinement description, Structure summary - Version 1.2: 2019-08-21
Changes: Data collection - Version 1.3: 2024-01-24
Changes: Data collection, Database references, Refinement description
