A Complete Model of the Cardiac Myosin Rod
Andreas, M.P., Korkmaz, E.N., Kirsch, C.J., Hargreaves, M., Kieffer, D.J., Ajay, G., Cui, Q., Rayment, I.To be published.
Experimental Data Snapshot
wwPDB Validation   3D Report Full Report
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Myosin-7 fused to GP7 and EB1 | 166 | Homo sapiens | Mutation(s): 0  Gene Names: MYH7, MYHCB | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P13848 (Bacillus phage phi29) Explore P13848  Go to UniProtKB:  P13848 | |||||
Find proteins for Q15691 (Homo sapiens) Explore Q15691  Go to UniProtKB:  Q15691 | |||||
PHAROS:  Q15691 GTEx:  ENSG00000101367  | |||||
Find proteins for P12883 (Homo sapiens) Explore P12883  Go to UniProtKB:  P12883 | |||||
PHAROS:  P12883 GTEx:  ENSG00000092054  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Groups | P12883P13848Q15691 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 2 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
MPD Query on MPD | E [auth A] F [auth A] G [auth A] H [auth B] I [auth B] | (4S)-2-METHYL-2,4-PENTANEDIOL C6 H14 O2 SVTBMSDMJJWYQN-YFKPBYRVSA-N | |||
SO4 Query on SO4 | J [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 37.107 | α = 81.79 |
b = 59.304 | β = 86.42 |
c = 86.548 | γ = 89.97 |
Software Name | Purpose |
---|---|
PHENIX | refinement |
HKL-2000 | data reduction |
HKL-2000 | data scaling |
PHASER | phasing |
Coot | model building |
REFMAC | refinement |
PDB_EXTRACT | data extraction |
Funding Organization | Location | Grant Number |
---|---|---|
National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI) | United States | R21 HL111237 |