6PFP

Crystal Structure of Amino Acids 1473-1536 of Human Beta Cardiac Myosin Fused to Gp7 and Eb1


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.20 Å
  • R-Value Free: 0.245 
  • R-Value Work: 0.194 
  • R-Value Observed: 0.196 

wwPDB Validation   3D Report Full Report


This is version 1.2 of the entry. See complete history


Literature

A Complete Model of the Cardiac Myosin Rod

Andreas, M.P.Korkmaz, E.N.Kirsch, C.J.Hargreaves, M.Kieffer, D.J.Ajay, G.Cui, Q.Rayment, I.

To be published.

Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Myosin-7 fused to GP7 and EB1
A, B, C, D
166Homo sapiensMutation(s): 0 
Gene Names: MYH7MYHCB
UniProt & NIH Common Fund Data Resources
Find proteins for P13848 (Bacillus phage phi29)
Explore P13848 
Go to UniProtKB:  P13848
Find proteins for Q15691 (Homo sapiens)
Explore Q15691 
Go to UniProtKB:  Q15691
PHAROS:  Q15691
GTEx:  ENSG00000101367 
Find proteins for P12883 (Homo sapiens)
Explore P12883 
Go to UniProtKB:  P12883
PHAROS:  P12883
GTEx:  ENSG00000092054 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupsP12883P13848Q15691
Sequence Annotations
Expand
  • Reference Sequence
Small Molecules
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.20 Å
  • R-Value Free: 0.245 
  • R-Value Work: 0.194 
  • R-Value Observed: 0.196 
  • Space Group: P 1
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 37.107α = 81.79
b = 59.304β = 86.42
c = 86.548γ = 89.97
Software Package:
Software NamePurpose
PHENIXrefinement
HKL-2000data reduction
HKL-2000data scaling
PHASERphasing
Cootmodel building
REFMACrefinement
PDB_EXTRACTdata extraction

Structure Validation

View Full Validation Report



Entry History & Funding Information

Deposition Data


Funding OrganizationLocationGrant Number
National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)United StatesR21 HL111237

Revision History  (Full details and data files)

  • Version 1.0: 2020-06-24
    Type: Initial release
  • Version 1.1: 2024-03-13
    Changes: Data collection, Database references
  • Version 1.2: 2024-04-03
    Changes: Refinement description