Download MendeleyCrystal Structure of Human Mucin-like Protocadherin EC1-2
Gray, M.E., Johnson, Z.R., Modak, D., Sotomayor, M.To be published.
6OAE
Crystal Structure of Human Mucin-like Protocadherin EC1-2
- PDB DOI: https://doi.org/10.2210/pdb6OAE/pdb
- Classification: CELL ADHESION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21
- Mutation(s): No
- Deposited: 2019-03-15 Released: 2020-03-18
- Funding Organization(s): National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.234
- R-Value Work: 0.197
- R-Value Observed: 0.199
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Mucin-like protocadherin | 215 | Homo sapiens | Mutation(s): 0 Gene Names: MUPCDH |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9HBB8 (Homo sapiens) Explore Q9HBB8 Go to UniProtKB: Q9HBB8 | |||||
PHAROS: Q9HBB8 GTEx: ENSG00000099834 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9HBB8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| TRS Query on TRS | B [auth A] | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL C4 H12 N O3 LENZDBCJOHFCAS-UHFFFAOYSA-O |  | ||
| CA (Subject of Investigation/LOI) Query on CA | C [auth A], D [auth A], E [auth A] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.234
- R-Value Work: 0.197
- R-Value Observed: 0.199
- Space Group: I 2 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 50.427 | α = 90 |
| b = 78.379 | β = 90 |
| c = 121.39 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2020-03-18 Deposition Author(s): Johnson, Z.R., Gray, M.E., Sotomayor, M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK) | United States | DK095811 |
Revision History (Full details and data files)
- Version 1.0: 2020-03-18
Type: Initial release - Version 1.1: 2023-10-11
Changes: Data collection, Database references, Derived calculations, Refinement description
