Crystal structure of CGD4-650 with compound BI2536
Dong, A., Lin, Y.L., Hou, D., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Vedadi, M., Hui, R., Structural Genomics Consortium (SGC)To be published.
Experimental Data Snapshot
wwPDB Validation   3D Report Full Report
Currently 6MF9 does not have a validation slider image.
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
ZnKn (C2HC)+Athook+bromo domain protein, Taf250, transcription initiation factor IID | 167 | Cryptosporidium parvum Iowa II | Mutation(s): 0  Gene Names: cgd4_650 | ||
UniProt | |||||
Find proteins for Q5CQH9 (Cryptosporidium parvum (strain Iowa II)) Explore Q5CQH9  Go to UniProtKB:  Q5CQH9 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q5CQH9 | ||||
Sequence AnnotationsExpand | |||||
|
Ligands 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
R78 Query on R78 | C [auth A], D [auth B] | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide C28 H39 N7 O3 XQVVPGYIWAGRNI-JOCHJYFZSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 41.785 | α = 90 |
b = 89.869 | β = 90 |
c = 95.635 | γ = 90 |
Software Name | Purpose |
---|---|
DENZO | data reduction |
SCALEPACK | data scaling |
REFMAC | refinement |
PDB_EXTRACT | data extraction |
BALBES | phasing |
View Full Validation Report
Currently 6MF9 does not have a validation slider image.