6LE3

Experimental Data Snapshot

wwPDB Validation 3D Report Full Report

This is version 1.1 of the entry. See complete history.

Literature

(2020) Acta Crystallogr F Struct Biol Commun 76: 228-234

PubMed Abstract:
Gluconate 5-dehydrogenase (Ga5DH; EC 1.1.1.69) from Lentibacter algarum (LaGa5DH) was recombinantly expressed in Escherichia coli and purified to homogeneity. The protein was crystallized and the crystal structure was solved at 2.1 Å resolution. The crystal belonged to the monoclinic system, with space group P1 and unit-cell parameters a = 55.42, b = 55.48, c = 79.16 Å, α = 100.51, β = 105.66, γ = 97.99°. The structure revealed LaGaDH to be a tetramer, with each subunit consisting of six α-helices and three antiparallel β-hairpins. LaGa5DH has high structural similarity to other Ga5DH proteins, demonstrating that this enzyme is highly conserved.

Organizational Affiliation

School of Life Sciences, Jilin University, Changchun, Jilin 130012, People's Republic of China.

Macromolecule Content

Macromolecules

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(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Gluconate 5-dehydrogenase	A [auth E], B [auth F], C [auth G], D [auth H]	263	Lentibacter algarum	Mutation(s): 0 Gene Names: SAMN05444486_10810
UniProt
Find proteins for A0A1H3NGY9 (Lentibacter algarum) Explore A0A1H3NGY9 Go to UniProtKB: A0A1H3NGY9
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	A0A1H3NGY9
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 1 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
ACE Query on ACE Download Ideal Coordinates CCD File SDF format, chain E SDF format, chain F SDF format, chain G [auth F] SDF format, chain H [auth F] SDF format, chain I [auth F] SDF format, chain J [auth G] SDF format, chain K [auth G] SDF format, chain L [auth G] SDF format, chain M [auth H] MOL2 format, chain E MOL2 format, chain F MOL2 format, chain G [auth F] MOL2 format, chain H [auth F] MOL2 format, chain I [auth F] MOL2 format, chain J [auth G] MOL2 format, chain K [auth G] MOL2 format, chain L [auth G] MOL2 format, chain M [auth H]	E F G [auth F] H [auth F] I [auth F] E, F, G [auth F], H [auth F], I [auth F], J [auth G], K [auth G], L [auth G], M [auth H]	ACETYL GROUP C₂ H₄ O IKHGUXGNUITLKF-UHFFFAOYSA-N		Interactions Focus chain E Focus chain F Focus chain G [auth F] Focus chain H [auth F] Focus chain I [auth F] Focus chain J [auth G] Focus chain K [auth G] Focus chain L [auth G] Focus chain M [auth H] Interactions & Density Focus chain E Focus chain F Focus chain G [auth F] Focus chain H [auth F] Focus chain I [auth F] Focus chain J [auth G] Focus chain K [auth G] Focus chain L [auth G] Focus chain M [auth H]