Download MendeleyCRYSTAL STRUCTURE OF CMY-OXA-427-HisTag BETA-LACTAMASE
Zavala, A., Naas, T., Bogaerts, P., Glupczynski, Y., Retailleau, P., Iorga, B.I.To be published.
6HUH
CRYSTAL STRUCTURE OF OXA-427 class D BETA-LACTAMASE
- PDB DOI: https://doi.org/10.2210/pdb6HUH/pdb
- Classification: HYDROLASE
- Organism(s): Klebsiella pneumoniae
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2018-10-08 Released: 2019-10-30
- Funding Organization(s): French National Research Agency
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.78 Å
- R-Value Free: 0.269
- R-Value Work: 0.205
- R-Value Observed: 0.208
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Beta-lactamase | 274 | Klebsiella pneumoniae | Mutation(s): 0 Gene Names: blaOXA-427, PKLPN57_278 EC: 3.5.2.6 |  | |
UniProt | |||||
Find proteins for A0A1Y6M6D7 (Klebsiella pneumoniae) Explore A0A1Y6M6D7 Go to UniProtKB: A0A1Y6M6D7 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A1Y6M6D7 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 Query on SO4 | C [auth A], D [auth A], E [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| KCX Query on KCX | A, B | L-PEPTIDE LINKING | C7 H14 N2 O4 |  | LYS |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.78 Å
- R-Value Free: 0.269
- R-Value Work: 0.205
- R-Value Observed: 0.208
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 143.79 | α = 90 |
| b = 42.58 | β = 114.37 |
| c = 99.71 | γ = 90 |
| Software Name | Purpose |
|---|---|
| BUSTER | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| MrBUMP | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2019-10-30 Deposition Author(s): Zavala, A., Retailleau, P., Bogaerts, P., Glupczynski, Y., Naas, T., Iorga, B.
| Funding Organization | Location | Grant Number |
|---|---|---|
| French National Research Agency | France | ANR-10-LABX-33 |
| French National Research Agency | France | ANR-14-JAMR-0002 |
Revision History (Full details and data files)
- Version 1.0: 2019-10-30
Type: Initial release - Version 1.1: 2024-01-24
Changes: Data collection, Database references, Refinement description
