Download MendeleyCrystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain
Kumar, S., Kandavelu, P., Rathod, P.K.To be published.
6CA8
Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain
- PDB DOI: https://doi.org/10.2210/pdb6CA8/pdb
- Classification: ISOMERASE
- Organism(s): Plasmodium falciparum
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2018-01-29 Released: 2019-02-06
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.33 Å
- R-Value Free: 0.223
- R-Value Work: 0.188
- R-Value Observed: 0.189
wwPDB Validation 3D Report Full Report
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| DNA topoisomerase 2 | 751 | Plasmodium falciparum | Mutation(s): 0 Gene Names: TopoII EC: 5.99.1.3 |  | |
UniProt | |||||
Find proteins for Q7Z2D0 (Plasmodium falciparum) Explore Q7Z2D0 Go to UniProtKB: Q7Z2D0 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q7Z2D0 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.33 Å
- R-Value Free: 0.223
- R-Value Work: 0.188
- R-Value Observed: 0.189
- Space Group: P 21 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 83.034 | α = 90 |
| b = 104.482 | β = 90 |
| c = 114.523 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2019-02-06 Deposition Author(s): Kumar, S., Kandavelu, P., Rathod, P.K.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | AI 093380 |
Revision History (Full details and data files)
- Version 1.0: 2019-02-06
Type: Initial release - Version 1.1: 2019-02-20
Changes: Author supporting evidence, Data collection - Version 1.2: 2019-12-18
Changes: Author supporting evidence - Version 1.3: 2024-03-13
Changes: Data collection, Database references
