Download MendeleyThe crystal structure of a beta-lactamase from Staphylococcus aureus subsp. aureus USA300_TCH1516
Tan, K., Wu, R., Endres, M., Joachimiak, A.To be published.
6WGR
The crystal structure of a beta-lactamase from Staphylococcus aureus subsp. aureus USA300_TCH1516
- PDB DOI: https://doi.org/10.2210/pdb6WGR/pdb
- Classification: HYDROLASE
- Organism(s): Staphylococcus aureus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2020-04-06 Released: 2020-04-15
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.88 Å
- R-Value Free: 0.206
- R-Value Work: 0.167
- R-Value Observed: 0.169
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Beta-lactamase | 260 | Staphylococcus aureus | Mutation(s): 0 Gene Names: blaZ, SAP015A_001, SUA_0014, SUC_0012, SUD_0013p2, SUI_0012p2, SUJ_0013p2, SUK_0013p2, SUP_0013 EC: 3.5.2.6 |  | |
UniProt | |||||
Find proteins for P00807 (Staphylococcus aureus) Explore P00807 Go to UniProtKB: P00807 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00807 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EPE Query on EPE | D [auth A], E [auth C], F [auth C] | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID C8 H18 N2 O4 S JKMHFZQWWAIEOD-UHFFFAOYSA-N |  | ||
| GOL Query on GOL | G [auth C] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.88 Å
- R-Value Free: 0.206
- R-Value Work: 0.167
- R-Value Observed: 0.169
- Space Group: P 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 52.357 | α = 75.625 |
| b = 52.505 | β = 81.053 |
| c = 89.662 | γ = 64.124 |
| Software Name | Purpose |
|---|---|
| SBC-Collect | data collection |
| PHENIX | refinement |
| HKL-3000 | phasing |
| HKL-3000 | data scaling |
| HKL-3000 | data reduction |
Entry History & Funding Information
Deposition Data
- Released Date: 2020-04-15 Deposition Author(s): Tan, K., Wu, R., Endres, M., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | HHSN272201700060C |
Revision History (Full details and data files)
- Version 1.0: 2020-04-15
Type: Initial release - Version 1.1: 2023-10-18
Changes: Data collection, Database references, Refinement description
