Download MendeleyMolecular characterization and three-dimensional structures of avian H8, H11, H14, H15 and swine H4 influenza virus hemagglutinins
Yang, H., Carney, P.J., Chang, J., Stevens, J.(2020) Heliyon 6: e04068
6V44
The crystal structure of hemagglutinin from swine influenza virus A/swine/Missouri/A01727926/2015
- PDB DOI: https://doi.org/10.2210/pdb6V44/pdb
- Classification: VIRAL PROTEIN
- Organism(s): Influenza A virus (A/swine/Missouri/A01727926/2015(H4N6))
- Expression System: Trichoplusia ni
- Mutation(s): No
- Deposited: 2019-11-27 Released: 2020-06-17
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.244
- R-Value Work: 0.203
- R-Value Observed: 0.205
wwPDB Validation 3D Report Full Report
Currently 6V44 does not have a validation slider image.
This is version 2.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Hemagglutinin HA1 chain | 332 | Influenza A virus (A/swine/Missouri/A01727926/2015(H4N6)) | Mutation(s): 0 Gene Names: HA |  | |
UniProt | |||||
Find proteins for A0A140D8S6 (Influenza A virus) Explore A0A140D8S6 Go to UniProtKB: A0A140D8S6 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A140D8S6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Hemagglutinin HA2 chain | 186 | Influenza A virus (A/swine/Missouri/A01727926/2015(H4N6)) | Mutation(s): 0 Gene Names: HA |  | |
UniProt | |||||
Find proteins for A0A140D8S6 (Influenza A virus) Explore A0A140D8S6 Go to UniProtKB: A0A140D8S6 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A140D8S6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Oligosaccharides
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | 2D Diagram | Glycosylation | 3D Interactions |
| alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | G, H, I | 6 |  | N-Glycosylation | |
Glycosylation Resources | |||||
GlyTouCan: G56014GC GlyCosmos: G56014GC GlyGen: G56014GC | |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | J [auth A], K [auth C], L [auth E] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.244
- R-Value Work: 0.203
- R-Value Observed: 0.205
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 68.973 | α = 90 |
| b = 240.005 | β = 119.86 |
| c = 68.953 | γ = 90 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data scaling |
| PHENIX | refinement |
| PDB_EXTRACT | data extraction |
| HKL-2000 | data reduction |
| PHASER | phasing |
Structure Validation
Currently 6V44 does not have a validation slider image.
Entry History
Deposition Data
- Released Date: 2020-06-17 Deposition Author(s): Yang, H., Stevens, J.
Revision History (Full details and data files)
- Version 1.0: 2020-06-17
Type: Initial release - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Derived calculations, Structure summary - Version 2.1: 2023-10-11
Changes: Data collection, Database references, Derived calculations, Refinement description, Structure summary
