Download MendeleyCrystal Structure of the Metallo-beta-Lactamase FIM-1 from Pseudomonas aeruginosa in the Mono-Zinc Form
Kim, Y., Hatzos-Skintges, C., Endres, M., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)To be published.
6V3Q
Crystal Structure of the Metallo-beta-Lactamase FIM-1 from Pseudomonas aeruginosa in the Mono-Zinc Form
- PDB DOI: https://doi.org/10.2210/pdb6V3Q/pdb
- Classification: HYDROLASE
- Organism(s): Pseudomonas aeruginosa
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2019-11-26 Released: 2020-01-15
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Free: 0.185
- R-Value Work: 0.165
- R-Value Observed: 0.166
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Metallo-beta-lactamase FIM-1 | 230 | Pseudomonas aeruginosa | Mutation(s): 0 Gene Names: blaFIM-1 |  | |
UniProt | |||||
Find proteins for K7SA42 (Pseudomonas aeruginosa) Explore K7SA42 Go to UniProtKB: K7SA42 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | K7SA42 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZN Query on ZN | C [auth A], D [auth B] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
| IPA Query on IPA | E [auth B] | ISOPROPYL ALCOHOL C3 H8 O KFZMGEQAYNKOFK-UHFFFAOYSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| OCS Query on OCS | A, B | L-PEPTIDE LINKING | C3 H7 N O5 S |  | CYS |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Free: 0.185
- R-Value Work: 0.165
- R-Value Observed: 0.166
- Space Group: P 32
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 128.109 | α = 90 |
| b = 128.109 | β = 90 |
| c = 41.42 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
| HKL-3000 | phasing |
| MOLREP | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2020-01-15 Deposition Author(s): Kim, Y., Hatzos-Skintges, C., Endres, M., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | -- |
Revision History (Full details and data files)
- Version 1.0: 2020-01-15
Type: Initial release - Version 1.1: 2024-04-03
Changes: Data collection, Database references, Derived calculations, Refinement description
