Download MendeleyscFv AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery
Hargreaves, D.To be published.
6EHX
scFv AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery
- PDB DOI: https://doi.org/10.2210/pdb6EHX/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Homo sapiens
- Expression System: Escherichia coli 'BL21-Gold(DE3)pLysS AG
- Mutation(s): No
- Deposited: 2017-09-15 Released: 2017-11-08
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.241
- R-Value Work: 0.207
- R-Value Observed: 0.209
wwPDB Validation 3D Report Full Report
This is version 2.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| scFv AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery | A [auth B] | 240 | Homo sapiens | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.241
- R-Value Work: 0.207
- R-Value Observed: 0.209
- Space Group: P 41 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 81.559 | α = 90 |
| b = 81.559 | β = 90 |
| c = 116.395 | γ = 90 |
| Software Name | Purpose |
|---|---|
| BUSTER | refinement |
| XDS | data reduction |
| XDS | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2017-11-08 Deposition Author(s): Hargreaves, D.
Revision History (Full details and data files)
- Version 1.0: 2017-11-08
Type: Initial release - Version 2.0: 2019-10-16
Changes: Atomic model, Data collection
