6AL5
COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB
- PDB DOI: https://doi.org/10.2210/pdb6AL5/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Homo sapiens
- Expression System: unidentified baculovirus, Homo sapiens
- Mutation(s): Yes 
- Deposited: 2017-08-07 Released: 2018-03-28 
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 3.00 Å
- R-Value Free: 0.263 
- R-Value Work: 0.189 
- R-Value Observed: 0.193 
This is version 2.1 of the entry. See complete history. 
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
B-lymphocyte antigen CD19 | 265 | Homo sapiens | Mutation(s): 1  Gene Names: CD19 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P15391 (Homo sapiens) Explore P15391  Go to UniProtKB:  P15391 | |||||
PHAROS:  P15391 GTEx:  ENSG00000177455  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P15391 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
B43 LIGHT CHAIN | B [auth L] | 218 | Homo sapiens | Mutation(s): 0  | |
UniProt | |||||
Find proteins for Q6P5S8 (Homo sapiens) Explore Q6P5S8  Go to UniProtKB:  Q6P5S8 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q6P5S8 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 3 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
B43 HEAVY CHAIN | C [auth H] | 233 | Homo sapiens | Mutation(s): 0  | |
UniProt | |||||
Find proteins for A8K008 (Homo sapiens) Explore A8K008  Go to UniProtKB:  A8K008 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | A8K008 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
Ligands 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
NAG Query on NAG | D [auth A], E [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |
Modified Residues 1 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Type | Formula | 2D Diagram | Parent |
PCA Query on PCA | C [auth H] | L-PEPTIDE LINKING | C5 H7 N O3 | GLN |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 3.00 Å
- R-Value Free: 0.263 
- R-Value Work: 0.189 
- R-Value Observed: 0.193 
- Space Group: P 21 21 21
Unit Cell:
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 64.8 | α = 90 |
b = 92.35 | β = 90 |
c = 146.99 | γ = 90 |
Software Name | Purpose |
---|---|
REFMAC | refinement |
XDS | data reduction |
XDS | data scaling |
PHASER | phasing |
Entry History 
Deposition Data
- Released Date: 2018-03-28  Deposition Author(s): Teplyakov, A., Obmolova, G., Gilliland, G.L.
Revision History (Full details and data files)
- Version 1.0: 2018-03-28
Type: Initial release - Version 1.1: 2018-05-02
Changes: Data collection, Database references - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Derived calculations, Polymer sequence, Structure summary - Version 2.1: 2023-10-04
Changes: Data collection, Database references, Refinement description, Structure summary