5Z11

Crystal Structure of Grass Carp CD8 alpha alpha Homodimers

PDB DOI: https://doi.org/10.2210/pdb5Z11/pdb

Classification: IMMUNE SYSTEM
Organism(s): Ctenopharyngodon idella
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2017-12-22 Released: 2018-04-11
Deposition Author(s): Wang, J.
Funding Organization(s): National Natural Science Foundation of China

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.35 Å
R-Value Free: 0.258
R-Value Work: 0.200
R-Value Observed: 0.203

wwPDB Validation 3D Report Full Report

This is version 1.0 of the entry. See complete history.

Literature

Crystal Structure of the Grass Carp CD8 alpha alpha Homodimers Indicates a Dramatic Evolution of CD8 from Ectotherms to Endotherms.

Wang, J., Zhang, L.

To be published.

Macromolecule Content

Total Structure Weight: 28.33 kDa
Atom Count: 1,647
Modelled Residue Count: 204
Deposited Residue Count: 256
Unique protein chains: 1

Macromolecules

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(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
CD8 alpha chain	A, B	128	Ctenopharyngodon idella	Mutation(s): 0
UniProt
Find proteins for C7FF18 (Ctenopharyngodon idella) Explore C7FF18 Go to UniProtKB: C7FF18
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	C7FF18
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 2.35 Å
R-Value Free: 0.258
R-Value Work: 0.200
R-Value Observed: 0.203
Space Group: P 4₁ 2₁ 2

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 47.91	α = 90
b = 47.91	β = 90
c = 242.97	γ = 90

Software Package:

Software Name	Purpose
REFMAC	refinement
HKL-2000	data reduction
HKL-2000	data scaling
PHASER	phasing

Structure Validation

View Full Validation Report

Entry History & Funding Information

Deposition Data

Released Date: 2018-04-11

Deposition Author(s):

Funding Organization	Location	Grant Number
National Natural Science Foundation of China	China	NO.31230074

Revision History (Full details and data files)

Version 1.0: 2018-04-11
Type: Initial release

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.