Download MendeleyCrystal structure of WNK3 kinase and CCT1 didomain in a unphosphorylated state
Pinkas, D.M., Daubner, G.M., Bufton, J.C., Bartual, S.G., Sanvitale, C.E., Alessi, D.R., Bullock, A.To be published.
5O2C
Crystal structure of WNK3 kinase and CCT1 didomain in a unphosphorylated state
- PDB DOI: https://doi.org/10.2210/pdb5O2C/pdb
- Classification: STRUCTURAL GENOMICS
- Organism(s): Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): No
- Deposited: 2017-05-19 Released: 2017-06-28
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Free: 0.254
- R-Value Work: 0.185
- R-Value Observed: 0.189
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Serine/threonine-protein kinase WNK3 | 380 | Homo sapiens | Mutation(s): 0 Gene Names: WNK3, KIAA1566, PRKWNK3 EC: 2.7.11.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9BYP7 (Homo sapiens) Explore Q9BYP7 Go to UniProtKB: Q9BYP7 | |||||
PHAROS: Q9BYP7 GTEx: ENSG00000196632 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9BYP7 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PEG Query on PEG | B [auth A] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N |  | ||
| GOL Query on GOL | C [auth A], D [auth A], E [auth A], F [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.40 Å
- R-Value Free: 0.254
- R-Value Work: 0.185
- R-Value Observed: 0.189
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 166.37 | α = 90 |
| b = 64.08 | β = 97.16 |
| c = 47.34 | γ = 90 |
| Software Name | Purpose |
|---|---|
| BUSTER | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2017-06-28 Deposition Author(s): Bartual, S.G., Pinkas, D.M., Bufton, J.C., Kupinska, K., Wang, D., Chalk, R., Berridge, G., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2017-06-28
Type: Initial release - Version 1.1: 2019-10-16
Changes: Data collection
