Download MendeleyHuman beta-Defensin 4: defensin without the "twist"
Adam, P., Marzenam, P., Jerry, A., Jacek, L.To be published.
5KI9
Crystal structure of human beta-defensin 4 (HBD4)
- PDB DOI: https://doi.org/10.2210/pdb5KI9/pdb
- Classification: ANTIMICROBIAL PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Membrane Protein: Yes OPM
- Deposited: 2016-06-16 Released: 2017-06-28
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 Å
- R-Value Free: 0.268
- R-Value Work: 0.230
- R-Value Observed: 0.234
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Beta-defensin 104 | 43 | Homo sapiens | Mutation(s): 0 Gene Names: DEFB104A, DEFB104, DEFB4, DEFB104B Membrane Entity: Yes |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8WTQ1 (Homo sapiens) Explore Q8WTQ1 Go to UniProtKB: Q8WTQ1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8WTQ1 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| TFA Query on TFA | E [auth A] | trifluoroacetic acid C2 H F3 O2 DTQVDTLACAAQTR-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | B [auth A], C [auth A], D [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MLY Query on MLY | A | L-PEPTIDE LINKING | C8 H18 N2 O2 |  | LYS |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 Å
- R-Value Free: 0.268
- R-Value Work: 0.230
- R-Value Observed: 0.234
- Space Group: P 43 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 41.704 | α = 90 |
| b = 41.704 | β = 90 |
| c = 52.945 | γ = 90 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data collection |
| HKL-2000 | data scaling |
| SHELX | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
Entry History
Deposition Data
- Released Date: 2017-06-28 Deposition Author(s): Jacek, L., Adam, P., Marzenam, P.
Revision History (Full details and data files)
- Version 1.0: 2017-06-28
Type: Initial release
