5J5K

CRYSTAL STRUCTURE OF AFMP4P IN COMPLEX WITH PALMITIC ACID

PDB DOI: https://doi.org/10.2210/pdb5J5K/pdb

Classification: LIPID BINDING PROTEIN
Organism(s): Aspergillus fumigatus Af293
Expression System: Komagataella pastoris DSMZ 70382
Mutation(s): No

Deposited: 2016-04-03 Released: 2017-04-05
Deposition Author(s): Zhang, H., Hao, Q.

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 1.95 Å
R-Value Free: 0.184
R-Value Work: 0.149
R-Value Observed: 0.151

wwPDB Validation 3D Report Full Report

This is version 1.3 of the entry. See complete history.

Literature

A Novel Class Of Virulence Factors In Penicillium Marneffei And Aspergillus Fumigatus Enhances Intracellular Survival In Monocytes By Arachidonic Acid Binding

Zhang, H., Hao, Q., Lam, W.H.

To be published.

Macromolecule Content

Total Structure Weight: 17.35 kDa
Atom Count: 1,259
Modelled Residue Count: 151
Deposited Residue Count: 164
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Uncharacterized protein	A	164	Aspergillus fumigatus Af293	Mutation(s): 0 Gene Names: AFUA_2G17630
UniProt
Find proteins for Q4WZA5 (Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)) Explore Q4WZA5 Go to UniProtKB: Q4WZA5
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q4WZA5
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 2 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
PLM Query on PLM Download Ideal Coordinates CCD File SDF format, chain C [auth A] MOL2 format, chain C [auth A]	C [auth A]	PALMITIC ACID C₁₆ H₃₂ O₂ IPCSVZSSVZVIGE-UHFFFAOYSA-N		Interactions Focus chain C [auth A] Interactions & Density Focus chain C [auth A]
MAN Query on MAN Download Ideal Coordinates CCD File SDF format, chain B [auth A] MOL2 format, chain B [auth A]	B [auth A]	alpha-D-mannopyranose C₆ H₁₂ O₆ WQZGKKKJIJFFOK-PQMKYFCFSA-N		Interactions Focus chain B [auth A] Interactions & Density Focus chain B [auth A]

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 1.95 Å
R-Value Free: 0.184
R-Value Work: 0.149
R-Value Observed: 0.151
Space Group: I 4 3 2

Unit Cell:

Length ( Å )	Angle ( ˚ )
a = 124.836	α = 90
b = 124.836	β = 90
c = 124.836	γ = 90

Software Package:

Software Name	Purpose
DENZO	data reduction
SCALEPACK	data scaling
PHASER	phasing
REFMAC	refinement

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2017-04-05

Deposition Author(s):

Zhang, H.

Hao, Q.

Revision History (Full details and data files)

Version 1.0: 2017-04-05
Type: Initial release
Version 1.1: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection, Derived calculations, Structure summary
Version 1.2: 2023-10-11
Changes: Data collection, Database references, Structure summary
Version 1.3: 2023-11-08
Changes: Refinement description

Prepare Data

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Deposit Data

Help and Resources

5J5K

CRYSTAL STRUCTURE OF AFMP4P IN COMPLEX WITH PALMITIC ACID

A Novel Class Of Virulence Factors In Penicillium Marneffei And Aspergillus Fumigatus Enhances Intracellular Survival In Monocytes By Arachidonic Acid Binding

Entity ID: 1

UniProt

Entity Groups

Sequence Annotations

Expand

Experimental Data

Structure Validation

Deposition Data

Revision History (Full details and data files)