Download MendeleyStructural and Functional Analysis of Chaperone Domain Insertion in Fkbp12
Zoldak, G., Knappe, T.A., Geitner, A.-J., Scholz, C., Dobbek, H., Schmid, F.X., Jakob, R.P.To be published.
5I7P
Crystal structure of Fkbp12-IF(SlyD), a chimeric protein of human Fkbp12 and the insert in flap domain of Ecoli SlyD
- PDB DOI: https://doi.org/10.2210/pdb5I7P/pdb
- Classification: ISOMERASE
- Organism(s): Homo sapiens, Escherichia coli
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): Yes
- Deposited: 2016-02-18 Released: 2017-03-08
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.248
- R-Value Work: 0.219
- R-Value Observed: 0.221
wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Peptidyl-prolyl cis-trans isomerase FKBP1A,FKBP-type peptidyl-prolyl cis-trans isomerase SlyD,Peptidyl-prolyl cis-trans isomerase FKBP1A | 161 | Homo sapiens, Escherichia coli | Mutation(s): 1 Gene Names: FKBP1A, FKBP1, FKBP12, slyD, b3349, JW3311 EC: 5.2.1.8 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P0A9K9 (Escherichia coli (strain K12)) Explore P0A9K9 Go to UniProtKB: P0A9K9 | |||||
Find proteins for P62942 (Homo sapiens) Explore P62942 Go to UniProtKB: P62942 | |||||
PHAROS: P62942 GTEx: ENSG00000088832 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Groups | P62942P0A9K9 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 Å
- R-Value Free: 0.248
- R-Value Work: 0.219
- R-Value Observed: 0.221
- Space Group: P 41 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 60.219 | α = 90 |
| b = 60.219 | β = 90 |
| c = 120.5 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2017-03-08 Deposition Author(s): Jakob, R.P., Knappe, T.A., Dobbek, H., Schmid, F.X.
Revision History (Full details and data files)
- Version 1.0: 2017-03-08
Type: Initial release - Version 1.1: 2024-01-10
Changes: Data collection, Database references, Refinement description
